13 days ago
Six-Month Run: NVDA stock has climbed 20.6% since mid-March, a 45.4% annualized pace, even as the S&P 500 wobbled under the Fed's rate hike and a 10-year Treasury yield near 5%.
Model Verdict: TIKR's model puts fair value at $643, implying 193% total return by early 2031.
Coverage Split: Nvidia stock carries 48 buy ratings, 10 outperforms, 2 holds, 2 no opinions and 1 sell, with a mean target of $328, 50% above the current price.
Supply Squeeze: Nvidia guided to roughly 70% revenue growth for fiscal 2028 on demand it calls supply-constrained, with cloud industry backlog above $2 trillion.
Nvidia (NVDA) stock has climbed 20.6% since mid-March, a 45.4% annualized pace, while the Federal Reserve's first rate hike in more than three years pushed the 10-year Treasury yield toward 5% and dragged the S&P 500 into back-to-back weekly declines. Most of the market treated the hike as a reason to sell. Nvidia stock kept climbing anyway.
#march #model #supply #since
Model Verdict: TIKR's model puts fair value at $643, implying 193% total return by early 2031.
Coverage Split: Nvidia stock carries 48 buy ratings, 10 outperforms, 2 holds, 2 no opinions and 1 sell, with a mean target of $328, 50% above the current price.
Supply Squeeze: Nvidia guided to roughly 70% revenue growth for fiscal 2028 on demand it calls supply-constrained, with cloud industry backlog above $2 trillion.
Nvidia (NVDA) stock has climbed 20.6% since mid-March, a 45.4% annualized pace, while the Federal Reserve's first rate hike in more than three years pushed the 10-year Treasury yield toward 5% and dragged the S&P 500 into back-to-back weekly declines. Most of the market treated the hike as a reason to sell. Nvidia stock kept climbing anyway.
#march #model #supply #since
13 days ago
An old Wall Street adage just got a fresh test.
"Don't fight the Fed" has guided generations of investors through rate cycles both gentle and brutal. This time, it came roaring back into the conversation after the central bank made its first major policy shift in more than three years.
Jim Cramer wasted no time translating what happened into plain language for viewers watching at home. His verdict landed within hours of the decision, and it was blunt enough to make anyone holding stocks in their portfolio pay very close attention.
Cramer delivered his warning on Sept. 16 on "Mad Money," just hours after the Federal Reserve raised its benchmark federal funds rate by a quarter percentage point to a range of 3.75% to 4%.
"If you buy stocks here, you're now officially fighting the Federal Reserve," Cramer said, invoking the old adage that ignoring it tends to hurt returns.
#wall
"Don't fight the Fed" has guided generations of investors through rate cycles both gentle and brutal. This time, it came roaring back into the conversation after the central bank made its first major policy shift in more than three years.
Jim Cramer wasted no time translating what happened into plain language for viewers watching at home. His verdict landed within hours of the decision, and it was blunt enough to make anyone holding stocks in their portfolio pay very close attention.
Cramer delivered his warning on Sept. 16 on "Mad Money," just hours after the Federal Reserve raised its benchmark federal funds rate by a quarter percentage point to a range of 3.75% to 4%.
"If you buy stocks here, you're now officially fighting the Federal Reserve," Cramer said, invoking the old adage that ignoring it tends to hurt returns.
#wall
15 days ago
PepsiCo (PEP) has gone nowhere for a year, down 1.8% over the past twelve months while the S&P 500 returned 16.6%. At about $135 a share it trades at 17.7 times earnings, against an S&P 500 median of 22.5. A big cash generator priced below the market is what value buyers hunt for, so is this discount impatience or a verdict?
PepsiCo sells snacks and drinks everywhere consumer staples get sold: grocery aisles, convenience and gas stations, and the away-from-home locations it keeps adding. That reach turns into cash: free cash flow over the trailing twelve months was $9.28 billion, a 5.0% yield.
None of the recent numbers look like a business in trouble. Revenue over the trailing twelve months grew 5.6%, and the operating margin is holding at 15.0% against an S&P 500 median of 18.6%. Management says global volumes grew in both foods and beverages in the first half of 2026, the fastest growth in volume since 2022.
Widen the window and the picture changes. PepsiCo's revenue grew 5.6% over the trailing twelve months against an S&P 500 median of 8.3%, and its three-year average is just 2.5% a year. The trailing twelve months ran hotter, but one window is not a pace, and the pace is what the market pays for.
The company lowered prices in the U.S. early in 2026 to get volume moving. Management says salty snacks went from falling volume to rising volume and PepsiCo gained share, but volume in the second quarter of 2026 fell short of what it expected, which it blames on a consumer hurt by higher gas prices and on delays executing the price investment at some customers. None of this is lost on the market: it is pricing a company that grows slowly and has just spent money trying to grow faster. The problem sits in North America, while the international business stayed strong.
#months #trailing
PepsiCo sells snacks and drinks everywhere consumer staples get sold: grocery aisles, convenience and gas stations, and the away-from-home locations it keeps adding. That reach turns into cash: free cash flow over the trailing twelve months was $9.28 billion, a 5.0% yield.
None of the recent numbers look like a business in trouble. Revenue over the trailing twelve months grew 5.6%, and the operating margin is holding at 15.0% against an S&P 500 median of 18.6%. Management says global volumes grew in both foods and beverages in the first half of 2026, the fastest growth in volume since 2022.
Widen the window and the picture changes. PepsiCo's revenue grew 5.6% over the trailing twelve months against an S&P 500 median of 8.3%, and its three-year average is just 2.5% a year. The trailing twelve months ran hotter, but one window is not a pace, and the pace is what the market pays for.
The company lowered prices in the U.S. early in 2026 to get volume moving. Management says salty snacks went from falling volume to rising volume and PepsiCo gained share, but volume in the second quarter of 2026 fell short of what it expected, which it blames on a consumer hurt by higher gas prices and on delays executing the price investment at some customers. None of this is lost on the market: it is pricing a company that grows slowly and has just spent money trying to grow faster. The problem sits in North America, while the international business stayed strong.
#months #trailing
18 days ago
One of the 11 jurors who wanted to find Massachusetts mom Lindsay Clancy not criminally responsible for killing her three children said the panel viewed the case as a chance to make things "better for other women" and families — a thought process that one legal ****** yst is calling "problematic."
"Even though we didn't know what was going on outside of our little bubble that we were in, we knew that this was a turning point, and this would be something that could change something to make it better for other women in the future, for other families," 65-year-old Clancy juror Paula Devlin told "CBS Saturday Morning" over the weekend. "You know, justice for those children is this never happening again."
According to Devlin, before the 11-1 deadlock that led to a mistrial, the jury had been split eight in favor of finding her not criminally responsible, two were undecided, and the holdout and one other juror were leaning toward a guilty verdict.
Lone Holdout Juror In Lindsay Clancy Trial Was Only Black Person On The Jury, Panelist Reveals: Report
"Devlin's statement is problematic," said Neama Rahmani, a Los Angeles-based trial attorney and legal ****** yst who has been following the case. "Jurors are supposed to decide cases solely based on the facts of that case. In the Clancy case, they were to decide whether she was criminally responsible."
#clancy #case
"Even though we didn't know what was going on outside of our little bubble that we were in, we knew that this was a turning point, and this would be something that could change something to make it better for other women in the future, for other families," 65-year-old Clancy juror Paula Devlin told "CBS Saturday Morning" over the weekend. "You know, justice for those children is this never happening again."
According to Devlin, before the 11-1 deadlock that led to a mistrial, the jury had been split eight in favor of finding her not criminally responsible, two were undecided, and the holdout and one other juror were leaning toward a guilty verdict.
Lone Holdout Juror In Lindsay Clancy Trial Was Only Black Person On The Jury, Panelist Reveals: Report
"Devlin's statement is problematic," said Neama Rahmani, a Los Angeles-based trial attorney and legal ****** yst who has been following the case. "Jurors are supposed to decide cases solely based on the facts of that case. In the Clancy case, they were to decide whether she was criminally responsible."
#clancy #case
18 days ago
If you or someone you know is having thoughts of suicide, please contact the National Suicide Prevention Lifeline at 1-800-273-TALK (8255).
Calls to repeal women's rights to vote are emerging from the online firestorm over the Lindsay Clancy trial, prompting Republican women to warn that the intraparty rhetoric could hurt the GOP.
"I think there's definitely a threat in the Republican Party right now," political and legal strategist Mehek Cooke told Fox News Digital.
The online calls to repeal the 19th Amendment come after Clancy's high-profile murder trial ended in a mistrial, with 11 of the 12 jurors favoring a verdict of not guilty by reason of insanity. Clancy admitted to killing her three children, but her defense argued she was not criminally responsible because she was suffering from postpartum psychosis.
Lindsay Clancy Mistrial Declared After Jury Deadlocks In Killings Of Her Three Children
#three #online
Calls to repeal women's rights to vote are emerging from the online firestorm over the Lindsay Clancy trial, prompting Republican women to warn that the intraparty rhetoric could hurt the GOP.
"I think there's definitely a threat in the Republican Party right now," political and legal strategist Mehek Cooke told Fox News Digital.
The online calls to repeal the 19th Amendment come after Clancy's high-profile murder trial ended in a mistrial, with 11 of the 12 jurors favoring a verdict of not guilty by reason of insanity. Clancy admitted to killing her three children, but her defense argued she was not criminally responsible because she was suffering from postpartum psychosis.
Lindsay Clancy Mistrial Declared After Jury Deadlocks In Killings Of Her Three Children
#three #online
20 days ago
Lil Durk remains in jail despite his Friday acquittal.
On 11 September, a Los Angeles federal jury found the rapper, whose real name is Durk Banks, not guilty of orchestrating a murder-for-hire plot that resulted in the death of a man in Los Angeles four years ago.
Prosecutors have confirmed he will remain in custody until his racketeering case, tied to the 2022 shooting death of Stephon Mack, is also resolved. That second trial on racketeering murder and firearms charges is scheduled for 5 October.
Longtime nemesis and fellow rapper 6ix9ine found a way to throw shade at Durk despite Chicago rapper's win in court.
6ix9ine had planned to throw a 'Lil Durk Going Away Party' in the event of a guilty verdict, and still held a celebration of sorts.
Posting a video on Instagram of him letting off fireworks and popping champagne, he reacted to the decision while mocking Durk about his deceased brother, Dontay 'DThang' Banks, and rapper King Von, who was signed to Durk's label, Only the Family.
#found
On 11 September, a Los Angeles federal jury found the rapper, whose real name is Durk Banks, not guilty of orchestrating a murder-for-hire plot that resulted in the death of a man in Los Angeles four years ago.
Prosecutors have confirmed he will remain in custody until his racketeering case, tied to the 2022 shooting death of Stephon Mack, is also resolved. That second trial on racketeering murder and firearms charges is scheduled for 5 October.
Longtime nemesis and fellow rapper 6ix9ine found a way to throw shade at Durk despite Chicago rapper's win in court.
6ix9ine had planned to throw a 'Lil Durk Going Away Party' in the event of a guilty verdict, and still held a celebration of sorts.
Posting a video on Instagram of him letting off fireworks and popping champagne, he reacted to the decision while mocking Durk about his deceased brother, Dontay 'DThang' Banks, and rapper King Von, who was signed to Durk's label, Only the Family.
#found
21 days ago
Lil Durk has been cleared of every charge in the federal murder-for-hire trial that drew packed courtrooms, celebrity spectators and crowds of supporters to downtown Los Angeles.
A federal jury found the 33-year-old Chicago rapper, whose legal name is Durk Banks, not guilty on September 11 after three days of deliberations. The case centered on an August 2022 attack targeting rapper Quando Rondo that instead killed Rondo's 24-year-old cousin, Saviay'a Robinson, according to The ******* ociated Press.
Prosecutors accused Durk of financing and directing the attack in retaliation for the 2020 killing of his close friend Dayvon "King Von" Bennett. Durk's lawyers argued that former ******* istant Kavon Grant organized the plot without the rapper's knowledge and attacked the credibility of cooperating witnesses who had reached plea agreements with the government.
Durk was not released after the verdict. He remains in federal custody because he faces a separate trial involving murder-related racketeering and firearms allegations, with jury selection currently scheduled to begin October 5.
Durk had faced five counts: conspiracy to commit stalking, stalking using a dangerous weapon, stalking resulting in death, conspiracy to use interstate commerce facilities to commit murder-for-hire resulting in death and use of interstate commerce facilities to commit murder-for-hire resulting in death.
#commit #stalking
A federal jury found the 33-year-old Chicago rapper, whose legal name is Durk Banks, not guilty on September 11 after three days of deliberations. The case centered on an August 2022 attack targeting rapper Quando Rondo that instead killed Rondo's 24-year-old cousin, Saviay'a Robinson, according to The ******* ociated Press.
Prosecutors accused Durk of financing and directing the attack in retaliation for the 2020 killing of his close friend Dayvon "King Von" Bennett. Durk's lawyers argued that former ******* istant Kavon Grant organized the plot without the rapper's knowledge and attacked the credibility of cooperating witnesses who had reached plea agreements with the government.
Durk was not released after the verdict. He remains in federal custody because he faces a separate trial involving murder-related racketeering and firearms allegations, with jury selection currently scheduled to begin October 5.
Durk had faced five counts: conspiracy to commit stalking, stalking using a dangerous weapon, stalking resulting in death, conspiracy to use interstate commerce facilities to commit murder-for-hire resulting in death and use of interstate commerce facilities to commit murder-for-hire resulting in death.
#commit #stalking
21 days ago
This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide and Crisis Lifeline at 988 or 800-273-TALK (8255).
An audience at a taping of Oprah Winfrey's podcast on Thursday applauded a call to support women like Lindsay Clancy who don't have "her privilege" after Clancy's murder trial ended in a mistrial.
Winfrey's show took place in the wake of Clancy's trial after she admitted to strangling her three children in 2023.
Last week, Judge William Sullivan declared a mistrial after jurors failed to reach a unanimous verdict on whether Clancy was criminally responsible for killing her children. Her defense argued that Clancy was suffering from postpartum psychosis at the time.
Rogan Shreds Supporters Of Lindsay Clancy, Says They Wouldn't Rally If A Father Were On Trial For Same Crime
#suicide
An audience at a taping of Oprah Winfrey's podcast on Thursday applauded a call to support women like Lindsay Clancy who don't have "her privilege" after Clancy's murder trial ended in a mistrial.
Winfrey's show took place in the wake of Clancy's trial after she admitted to strangling her three children in 2023.
Last week, Judge William Sullivan declared a mistrial after jurors failed to reach a unanimous verdict on whether Clancy was criminally responsible for killing her children. Her defense argued that Clancy was suffering from postpartum psychosis at the time.
Rogan Shreds Supporters Of Lindsay Clancy, Says They Wouldn't Rally If A Father Were On Trial For Same Crime
#suicide
22 days ago
Duane "Keffe D" Davis is pushing back hard against his murder conviction, vowing to fight the verdict in court.
In his first interview after a Las Vegas jury found him guilty of first-degree murder with use of a deadly weapon in the 1996 killing of 2Pac Shakur, Davis spoke to The Hollywood Reporter shortly after the verdict.
"Shit, I ain't worried. I'm getting out on an appeal. We already filed it before the trial even started. They violated my civil rights!" Davis said.
"I'm innocent, man. They got an innocent man sitting in jail. I've got two grandsons that are going to the pros in football," Davis continued. "They All-Americans—one of them is in high school. He has 25 scholarship offers, and the other one is in college. And when they get their millions, they're coming to get me out of here."
COMPLEX SHOP: Shop the brands you love, anytime and anywhere. Uncover what's next. Buy. Collect. Obsess.
#shop #keffe
In his first interview after a Las Vegas jury found him guilty of first-degree murder with use of a deadly weapon in the 1996 killing of 2Pac Shakur, Davis spoke to The Hollywood Reporter shortly after the verdict.
"Shit, I ain't worried. I'm getting out on an appeal. We already filed it before the trial even started. They violated my civil rights!" Davis said.
"I'm innocent, man. They got an innocent man sitting in jail. I've got two grandsons that are going to the pros in football," Davis continued. "They All-Americans—one of them is in high school. He has 25 scholarship offers, and the other one is in college. And when they get their millions, they're coming to get me out of here."
COMPLEX SHOP: Shop the brands you love, anytime and anywhere. Uncover what's next. Buy. Collect. Obsess.
#shop #keffe
22 days ago
As Norway continues to follow the ongoing case involving Marius Borg Høiby, with a verdict expected on June 15, concern over Princess Mette-Marit's health has also intensified. The crown princess, who is reportedly on a waiting list for a lung transplant, was notably absent from a milestone event that holds special meaning for both her and her husband, Crown Prince Haakon.
On June 11, Haakon attended the 25th anniversary celebration of the Crown Prince and Crown Princess's Fund, a charitable initiative established on the day of their wedding and one that has since become a cornerstone of the couple's public work.
This year's event carried particular emotional significance. For the first time, Princess Mette-Marit was unable to attend the annual celebration of the fund that was created as a direct result of her marriage to Haakon. Her fragile health prevented her from taking part in an occasion they have always hosted together, adding a poignant note to an event that represents a major part of their shared legacy.
Her last public appearance was on Norway's National Day, May 17, when she appeared visibly weakened and was seen relying on supplemental oxygen.
Crown Prince Haakon married Mette-Marit Tjessem Høiby on August 25, 2001, at Oslo Cathedral in a ceremony attended by royals from across Europe, including Spain's Queen Sofía and the then-Prince Felipe.
#mette #princess #june #Health
On June 11, Haakon attended the 25th anniversary celebration of the Crown Prince and Crown Princess's Fund, a charitable initiative established on the day of their wedding and one that has since become a cornerstone of the couple's public work.
This year's event carried particular emotional significance. For the first time, Princess Mette-Marit was unable to attend the annual celebration of the fund that was created as a direct result of her marriage to Haakon. Her fragile health prevented her from taking part in an occasion they have always hosted together, adding a poignant note to an event that represents a major part of their shared legacy.
Her last public appearance was on Norway's National Day, May 17, when she appeared visibly weakened and was seen relying on supplemental oxygen.
Crown Prince Haakon married Mette-Marit Tjessem Høiby on August 25, 2001, at Oslo Cathedral in a ceremony attended by royals from across Europe, including Spain's Queen Sofía and the then-Prince Felipe.
#mette #princess #june #Health
22 days ago
1
Manchester United head coach Michael Carrick praised Benjamin Sesko's role in the team as he outlined what sets the striker apart.
Sesko scored United's third of a 4-0 victory over Sabah in the Champions League on Thursday evening.
Matheus Cunha, Bruno Fernandes and Lisandro Martinez also got on the scoresheet. After the final whistle, Carrick spoke to reporters and shared his verdict on the game.
Carrick said of Sesko, "Definitely offers a different kind of threat."
#manchester #united #michael
Manchester United head coach Michael Carrick praised Benjamin Sesko's role in the team as he outlined what sets the striker apart.
Sesko scored United's third of a 4-0 victory over Sabah in the Champions League on Thursday evening.
Matheus Cunha, Bruno Fernandes and Lisandro Martinez also got on the scoresheet. After the final whistle, Carrick spoke to reporters and shared his verdict on the game.
Carrick said of Sesko, "Definitely offers a different kind of threat."
#manchester #united #michael
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22 days ago
Aryna Sabalenka's tense exchanges with reporters have caused quite a stir at this year's US Open.
The world number one fielded several questions about her off-court commitments, and one reporter even asked her about the 'parties' she attended before the US Open.
Sabalenka shut down any suggestions that she wasn't focused, seemingly growing tired of the narrative.
Serena Williams' former coach, Patrick Mouratoglou, has now delivered his verdict on Sabalenka's relationship with the media.
Mouratoglou said the following on Instagram.
#mouratoglou #aryna #williams
The world number one fielded several questions about her off-court commitments, and one reporter even asked her about the 'parties' she attended before the US Open.
Sabalenka shut down any suggestions that she wasn't focused, seemingly growing tired of the narrative.
Serena Williams' former coach, Patrick Mouratoglou, has now delivered his verdict on Sabalenka's relationship with the media.
Mouratoglou said the following on Instagram.
#mouratoglou #aryna #williams
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22 days ago
Spencer Pratt is seemingly making his feelings known about the Lindsay Clancy case following the mistrial in the Massachusetts mother's murder trial.
Pratt, 43, appeared to reference the case in a post on X on Thursday, September 10, days after a jury was unable to reach a unanimous verdict on whether Clancy, 36, should be held criminally responsible for killing her three children.
"Shout out to my mom for not strangling me to death with an exercise band when I was an infant," the Hills alum, who unsuccessfully ran for mayor of Los Angeles earlier this year, wrote. "You're the best, ma!"
Facebook/Lindsay Marie Clancy
Clancy was charged with murdering her children, Cora, 5, Dawson, 3, and Callan, 8 months, at the family's Duxbury, Massachusetts, home in January 2023. Her defense did not dispute that she killed the children but argued that she was suffering from postpartum psychosis and should be found not guilty by reason of insanity. Prosecutors maintained that Clancy understood the wrongfulness of her actions.
#pratt #lindsay #massachusetts #shout
Pratt, 43, appeared to reference the case in a post on X on Thursday, September 10, days after a jury was unable to reach a unanimous verdict on whether Clancy, 36, should be held criminally responsible for killing her three children.
"Shout out to my mom for not strangling me to death with an exercise band when I was an infant," the Hills alum, who unsuccessfully ran for mayor of Los Angeles earlier this year, wrote. "You're the best, ma!"
Facebook/Lindsay Marie Clancy
Clancy was charged with murdering her children, Cora, 5, Dawson, 3, and Callan, 8 months, at the family's Duxbury, Massachusetts, home in January 2023. Her defense did not dispute that she killed the children but argued that she was suffering from postpartum psychosis and should be found not guilty by reason of insanity. Prosecutors maintained that Clancy understood the wrongfulness of her actions.
#pratt #lindsay #massachusetts #shout
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24 days ago
The Ballon d'Or is widely considered the most prestigious individual award in professional football. While all eyes typically focus on the men's player award, there are plenty of other trophies up for grabs as the football world descends upon London two months from now.
The nominees for the 2026 edition of the coach's award have now been made public. Ten candidates now await the verdict as football decides who will receive the one trophy that will
Whoever wins this award deserves to be considered the best coach of 2026.
They're the best coaches in the world! Let's sum up the nominees!
follow our live on https://t.co/tzQSMLcpjk#ba... pic.twitter.com/BlqHkql2kZ
Here is the breakdown of who is nominated (and the team they currently work for):
#they 're
The nominees for the 2026 edition of the coach's award have now been made public. Ten candidates now await the verdict as football decides who will receive the one trophy that will
Whoever wins this award deserves to be considered the best coach of 2026.
They're the best coaches in the world! Let's sum up the nominees!
follow our live on https://t.co/tzQSMLcpjk#ba... pic.twitter.com/BlqHkql2kZ
Here is the breakdown of who is nominated (and the team they currently work for):
#they 're
24 days ago
Bologna coach Domenico Tedesco was given a two-match ban and President Joey Saputo suspended until September 30 for insulting the referee, with Atalanta midfielder Gianluca Gaetano also punished.
The Lega Serie A disciplinary commission verdicts are in after the Week 3 matches were completed on Monday evening.
Bologna did not take their 2-2 draw with Sassuolo well, and are going to have to do without two of their chiefs going forward.
BOLOGNA, ITALY – SEPTEMBER 6: Domenico Tedesco manager of Bologna FC 1909 looks on during the Serie A match between Bologna FC and US Sassuolo at Stadio Renato Dall'Ara on September 6, 2026 in Bologna, Italy. (Photo by Gabriele Maltinti/Getty Images)
Tedesco was sent off from the touchline for dissent and it seems continued his protests in the tunnel after the match.
#september #match
The Lega Serie A disciplinary commission verdicts are in after the Week 3 matches were completed on Monday evening.
Bologna did not take their 2-2 draw with Sassuolo well, and are going to have to do without two of their chiefs going forward.
BOLOGNA, ITALY – SEPTEMBER 6: Domenico Tedesco manager of Bologna FC 1909 looks on during the Serie A match between Bologna FC and US Sassuolo at Stadio Renato Dall'Ara on September 6, 2026 in Bologna, Italy. (Photo by Gabriele Maltinti/Getty Images)
Tedesco was sent off from the touchline for dissent and it seems continued his protests in the tunnel after the match.
#september #match
25 days ago
On August 5, Vaxcyte (NASDAQ:PCVX) reported second-quarter results that read less like a snapshot of today and more like a countdown to a verdict. The clinical-stage vaccine maker has no product on the market yet, but its three late-stage trials for its lead pneumococcal candidate are now fully enrolled, with the first major readout due before year-end. Add a net loss that nearly doubled and a boardroom that just brought in two vaccine-industry veterans, and you have a company betting its near-term story on data still to come.
Vaxcyte's three Phase 3 studies of VAX-31, its next-generation pneumococcal conjugate vaccine, have dosed 6,191 adults combined, with roughly 3,500 of them receiving the actual candidate. The largest, OPUS-1, put 4,049 participants through head-to-head comparisons against Prevnar 20 and Capvaxive, the two shots VAX-31 needs to beat to earn a spot in the standard vaccination schedule. Data on safety, tolerability, and immune response from that trial are due in the fourth quarter of 2026, with results from OPUS-2 and OPUS-3 following in the first half of 2027.
A separate Phase 2 study testing VAX-31 in infants, covering both the primary immunization series and a booster dose, is on a similar timeline. In June, Vaxcyte also dosed the first participants in a Phase 1 study of VAX-A1, aimed at preventing disease from Group A Streptococcus, with topline data expected in the second half of 2027. As of June 30, cash and investments stood at $2.5 billion, up from $2.44 billion at the end of 2025, and the board added Dr. Moncef Slaoui, previously chief scientific advisor to Operation Warp Speed and a three-decade GSK veteran, alongside Dr. John Markels, the former president of Merck's global vaccines business.
None of that pipeline progress comes cheap. Vaxcyte's net loss for the quarter ended June 30 was $284.3 million, up from $166.6 million in the same period a year earlier, and the increase shows up on both sides of the ledger. R&D spending rose to $267.9 million from $194.2 million, driven by manufacturing work to prepare for a possible launch and by the cost of running three simultaneous Phase 3 trials at once. G&A expenses climbed too, to $34.9 million from $32 million, largely from adding headcount.
Because Vaxcyte has no approved product generating sales, every one of those dollars comes straight off the balance sheet. The calendar adds pressure of its own: even a clean OPUS-1 readout in the fourth quarter of 2026 still leaves the OPUS-2 and OPUS-3 results, plus a required manufacturing consistency study, sitting in the first half of 2027, pushing any license application and launch well beyond that. The newer VAX-A1 program is earlier still, with its second stage contingent on a safety board signing off on the first.
#phase
Vaxcyte's three Phase 3 studies of VAX-31, its next-generation pneumococcal conjugate vaccine, have dosed 6,191 adults combined, with roughly 3,500 of them receiving the actual candidate. The largest, OPUS-1, put 4,049 participants through head-to-head comparisons against Prevnar 20 and Capvaxive, the two shots VAX-31 needs to beat to earn a spot in the standard vaccination schedule. Data on safety, tolerability, and immune response from that trial are due in the fourth quarter of 2026, with results from OPUS-2 and OPUS-3 following in the first half of 2027.
A separate Phase 2 study testing VAX-31 in infants, covering both the primary immunization series and a booster dose, is on a similar timeline. In June, Vaxcyte also dosed the first participants in a Phase 1 study of VAX-A1, aimed at preventing disease from Group A Streptococcus, with topline data expected in the second half of 2027. As of June 30, cash and investments stood at $2.5 billion, up from $2.44 billion at the end of 2025, and the board added Dr. Moncef Slaoui, previously chief scientific advisor to Operation Warp Speed and a three-decade GSK veteran, alongside Dr. John Markels, the former president of Merck's global vaccines business.
None of that pipeline progress comes cheap. Vaxcyte's net loss for the quarter ended June 30 was $284.3 million, up from $166.6 million in the same period a year earlier, and the increase shows up on both sides of the ledger. R&D spending rose to $267.9 million from $194.2 million, driven by manufacturing work to prepare for a possible launch and by the cost of running three simultaneous Phase 3 trials at once. G&A expenses climbed too, to $34.9 million from $32 million, largely from adding headcount.
Because Vaxcyte has no approved product generating sales, every one of those dollars comes straight off the balance sheet. The calendar adds pressure of its own: even a clean OPUS-1 readout in the fourth quarter of 2026 still leaves the OPUS-2 and OPUS-3 results, plus a required manufacturing consistency study, sitting in the first half of 2027, pushing any license application and launch well beyond that. The newer VAX-A1 program is earlier still, with its second stage contingent on a safety board signing off on the first.
#phase
26 days ago
The Serie A weekend is now over, and with today's two matches, the third round of the league will be as well. We are still only in the very early stages of this season, but a few verdicts have already come in.
Watch the entire Serie BKT live with LaB Channel on OneFootball: subscribe for just €9.99 a month!
We know, for example, that as predicted, Inter are still the team to beat. It was already clear on paper, but the pitch has confirmed it. Three wins from three matches - nothing extraordinary so far - plus the icing on the cake of that crazy comeback against Napoli: an exciting run, top of the table alongside Roma, and the feeling, this time for real, of having not quite two full teams but at least plenty of quality alternatives available.
Against the Azzurri, Chivu called on Thuram, Curtis Jones, Carlos Augusto, Çalhanoglu and Bonny from the bench, managing to turn around the 0-2 lead Allegri had built. Just a few days before their Champions League opener, the Romanian coach allowed himself the luxury of rotation against the runners-up of Italy, and still came away with three points (however hard-fought they were).
This opening stretch of Serie A has also told us that the two genuine challengers to Inter in the Scudetto race seem to be Roma and Como, with Juve and Milan still in the midst of a full revamp and a Napoli side that is changing its identity and already sits 6 points off the top.
#three #Inter #napoli #league
Watch the entire Serie BKT live with LaB Channel on OneFootball: subscribe for just €9.99 a month!
We know, for example, that as predicted, Inter are still the team to beat. It was already clear on paper, but the pitch has confirmed it. Three wins from three matches - nothing extraordinary so far - plus the icing on the cake of that crazy comeback against Napoli: an exciting run, top of the table alongside Roma, and the feeling, this time for real, of having not quite two full teams but at least plenty of quality alternatives available.
Against the Azzurri, Chivu called on Thuram, Curtis Jones, Carlos Augusto, Çalhanoglu and Bonny from the bench, managing to turn around the 0-2 lead Allegri had built. Just a few days before their Champions League opener, the Romanian coach allowed himself the luxury of rotation against the runners-up of Italy, and still came away with three points (however hard-fought they were).
This opening stretch of Serie A has also told us that the two genuine challengers to Inter in the Scudetto race seem to be Roma and Como, with Juve and Milan still in the midst of a full revamp and a Napoli side that is changing its identity and already sits 6 points off the top.
#three #Inter #napoli #league
26 days ago
Nico Rosberg says it is "not feasible" for Ferrari to prioritise Lewis Hamilton over Charles Leclerc in the 2026 ***** le race, in a verdict that directly counters Hamilton's push for team orders at Ferrari.
Speaking to Sky Sports F1 following qualifying at the Italian Grand Prix, Rosberg addressed suggestions that Ferrari should back the seven-time champion in the ***** le fight. "They can't do that," said Rosberg, who was partnered with Hamilton at Mercedes from 2013 to 2016. "They have two No. 1 drivers, both on a similar level. You cannot, now in the middle of the season, put everything just working towards Lewis. It's way too early, and that doesn't make sense."
Rosberg acknowledged that the internal fighting has been costing Hamilton championship points, but insisted the team simply has no alternative. "Of course, it costs them performance, and Lewis championship points eventually, but the team cannot do that at this stage against Leclerc. It's not feasible," he added.
Rosberg's verdict carries particular weight because he lived through the exact arrangement Hamilton is now demanding. Hamilton has called for rules of engagement similar to his time at Mercedes with Rosberg, as GPblog reported on Sunday.
That famous document, created by then-Mercedes strategist James Vowles, was designed to prevent on-track clashes between Hamilton and Rosberg during their consecutive fierce ***** le fights between 2014 and 2016.
#hamilton #team
Speaking to Sky Sports F1 following qualifying at the Italian Grand Prix, Rosberg addressed suggestions that Ferrari should back the seven-time champion in the ***** le fight. "They can't do that," said Rosberg, who was partnered with Hamilton at Mercedes from 2013 to 2016. "They have two No. 1 drivers, both on a similar level. You cannot, now in the middle of the season, put everything just working towards Lewis. It's way too early, and that doesn't make sense."
Rosberg acknowledged that the internal fighting has been costing Hamilton championship points, but insisted the team simply has no alternative. "Of course, it costs them performance, and Lewis championship points eventually, but the team cannot do that at this stage against Leclerc. It's not feasible," he added.
Rosberg's verdict carries particular weight because he lived through the exact arrangement Hamilton is now demanding. Hamilton has called for rules of engagement similar to his time at Mercedes with Rosberg, as GPblog reported on Sunday.
That famous document, created by then-Mercedes strategist James Vowles, was designed to prevent on-track clashes between Hamilton and Rosberg during their consecutive fierce ***** le fights between 2014 and 2016.
#hamilton #team
27 days ago
On August 5, Vaxcyte (NASDAQ:PCVX) reported second-quarter results that read less like a snapshot of today and more like a countdown to a verdict. The clinical-stage vaccine maker has no product on the market yet, but its three late-stage trials for its lead pneumococcal candidate are now fully enrolled, with the first major readout due before year-end. Add a net loss that nearly doubled and a boardroom that just brought in two vaccine-industry veterans, and you have a company betting its near-term story on data still to come.
Vaxcyte's three Phase 3 studies of VAX-31, its next-generation pneumococcal conjugate vaccine, have dosed 6,191 adults combined, with roughly 3,500 of them receiving the actual candidate. The largest, OPUS-1, put 4,049 participants through head-to-head comparisons against Prevnar 20 and Capvaxive, the two shots VAX-31 needs to beat to earn a spot in the standard vaccination schedule. Data on safety, tolerability, and immune response from that trial are due in the fourth quarter of 2026, with results from OPUS-2 and OPUS-3 following in the first half of 2027.
A separate Phase 2 study testing VAX-31 in infants, covering both the primary immunization series and a booster dose, is on a similar timeline. In June, Vaxcyte also dosed the first participants in a Phase 1 study of VAX-A1, aimed at preventing disease from Group A Streptococcus, with topline data expected in the second half of 2027. As of June 30, cash and investments stood at $2.5 billion, up from $2.44 billion at the end of 2025, and the board added Dr. Moncef Slaoui, previously chief scientific advisor to Operation Warp Speed and a three-decade GSK veteran, alongside Dr. John Markels, the former president of Merck's global vaccines business.
None of that pipeline progress comes cheap. Vaxcyte's net loss for the quarter ended June 30 was $284.3 million, up from $166.6 million in the same period a year earlier, and the increase shows up on both sides of the ledger. R&D spending rose to $267.9 million from $194.2 million, driven by manufacturing work to prepare for a possible launch and by the cost of running three simultaneous Phase 3 trials at once. G&A expenses climbed too, to $34.9 million from $32 million, largely from adding headcount.
Because Vaxcyte has no approved product generating sales, every one of those dollars comes straight off the balance sheet. The calendar adds pressure of its own: even a clean OPUS-1 readout in the fourth quarter of 2026 still leaves the OPUS-2 and OPUS-3 results, plus a required manufacturing consistency study, sitting in the first half of 2027, pushing any license application and launch well beyond that. The newer VAX-A1 program is earlier still, with its second stage contingent on a safety board signing off on the first.
#opus #data
Vaxcyte's three Phase 3 studies of VAX-31, its next-generation pneumococcal conjugate vaccine, have dosed 6,191 adults combined, with roughly 3,500 of them receiving the actual candidate. The largest, OPUS-1, put 4,049 participants through head-to-head comparisons against Prevnar 20 and Capvaxive, the two shots VAX-31 needs to beat to earn a spot in the standard vaccination schedule. Data on safety, tolerability, and immune response from that trial are due in the fourth quarter of 2026, with results from OPUS-2 and OPUS-3 following in the first half of 2027.
A separate Phase 2 study testing VAX-31 in infants, covering both the primary immunization series and a booster dose, is on a similar timeline. In June, Vaxcyte also dosed the first participants in a Phase 1 study of VAX-A1, aimed at preventing disease from Group A Streptococcus, with topline data expected in the second half of 2027. As of June 30, cash and investments stood at $2.5 billion, up from $2.44 billion at the end of 2025, and the board added Dr. Moncef Slaoui, previously chief scientific advisor to Operation Warp Speed and a three-decade GSK veteran, alongside Dr. John Markels, the former president of Merck's global vaccines business.
None of that pipeline progress comes cheap. Vaxcyte's net loss for the quarter ended June 30 was $284.3 million, up from $166.6 million in the same period a year earlier, and the increase shows up on both sides of the ledger. R&D spending rose to $267.9 million from $194.2 million, driven by manufacturing work to prepare for a possible launch and by the cost of running three simultaneous Phase 3 trials at once. G&A expenses climbed too, to $34.9 million from $32 million, largely from adding headcount.
Because Vaxcyte has no approved product generating sales, every one of those dollars comes straight off the balance sheet. The calendar adds pressure of its own: even a clean OPUS-1 readout in the fourth quarter of 2026 still leaves the OPUS-2 and OPUS-3 results, plus a required manufacturing consistency study, sitting in the first half of 2027, pushing any license application and launch well beyond that. The newer VAX-A1 program is earlier still, with its second stage contingent on a safety board signing off on the first.
#opus #data
28 days ago
On a cold November morning, designer Isaac Mizrahi gets up, leaves his apartment, and trudges to the corner newsstand to pick up a copy of Women's Wear Daily. It's the day after Mizrahi's Spring/Summer 1994 show, and the ink on the reviews is still wet. Reading from the pages, he quotes, "'His usually great color sense failed him, his fabric sense failed him, and certainly, his sense of how a modern woman dresses after 8 p.m. failed him." The verdict is withering. Mizrahi, one of the great artists of '90s ready-to-wear fashion, has been tossed out. Disgraced. Lightly "cancelled," as some might call it these days.
Douglas Keeve's sublime 1995 documentary, "Unzipped," follows Mizrahi in the aftermath of a train wreck, piecing his reputation back together with his next collection, attempting to make something beautiful from the rubble. We find Mizrahi's world in grayscale, drained of color in the wake of critical and cultural failure. Then, the opening notes of Sandra Bernhard's 1994 cover of Sylvester's "You Make Me Feel (Mighty Real)" cue the pigmentation, cascading over bright images of models in fittings, garments hanging from racks, and plenty of DayGlo faux furs. In her version, Bernhard alters the lyrics to pay tribute to Sylvester, whose untimely death left an immense legacy. "Sylvester, sister," Bernhard coos, "You were so beautiful, you were so fragile, you were so . . . real."
But just before Bernhard finishes the word, the song fades to silence, as if to say that realness — genuine authenticity in your life and work, at the cost of criticism — will always be snuffed out before it can be fully appreciated. That is the price of beauty. What is up must always come down.
(Janus Films) Isaac Mizrahi in "Unzipped"
After years in cinematic obscurity — the film hasn't been readily available outside of the eBay market in decades — "Unzipped" will return to theaters later this month, with a loving 4K restoration from Janus Films, just as another fashion-world controversy is heating up. Earlier this week, the Metropolitan Museum of Art declared it would no longer proceed with its Costume Institute's upcoming exhibition honoring John Galliano, scheduled to debut next year. When the scrapped "John Galliano: Horizons" was announced in July, the exhibition was immediately met with an outpouring of criticism. Detractors accused the museum of being tone deaf, citing a 2011 video of Galliano going on a drunken antisemitic and racist rant at a Paris bar, for which Galliano was promptly ousted from his spot as creative director at Dior. Following the video surfacing, Galliano apologized, went to rehab, and, over the last few years, experienced a brand resurgence that some would call a whitewashing.
#mizrahi #bernhard #sense
Douglas Keeve's sublime 1995 documentary, "Unzipped," follows Mizrahi in the aftermath of a train wreck, piecing his reputation back together with his next collection, attempting to make something beautiful from the rubble. We find Mizrahi's world in grayscale, drained of color in the wake of critical and cultural failure. Then, the opening notes of Sandra Bernhard's 1994 cover of Sylvester's "You Make Me Feel (Mighty Real)" cue the pigmentation, cascading over bright images of models in fittings, garments hanging from racks, and plenty of DayGlo faux furs. In her version, Bernhard alters the lyrics to pay tribute to Sylvester, whose untimely death left an immense legacy. "Sylvester, sister," Bernhard coos, "You were so beautiful, you were so fragile, you were so . . . real."
But just before Bernhard finishes the word, the song fades to silence, as if to say that realness — genuine authenticity in your life and work, at the cost of criticism — will always be snuffed out before it can be fully appreciated. That is the price of beauty. What is up must always come down.
(Janus Films) Isaac Mizrahi in "Unzipped"
After years in cinematic obscurity — the film hasn't been readily available outside of the eBay market in decades — "Unzipped" will return to theaters later this month, with a loving 4K restoration from Janus Films, just as another fashion-world controversy is heating up. Earlier this week, the Metropolitan Museum of Art declared it would no longer proceed with its Costume Institute's upcoming exhibition honoring John Galliano, scheduled to debut next year. When the scrapped "John Galliano: Horizons" was announced in July, the exhibition was immediately met with an outpouring of criticism. Detractors accused the museum of being tone deaf, citing a 2011 video of Galliano going on a drunken antisemitic and racist rant at a Paris bar, for which Galliano was promptly ousted from his spot as creative director at Dior. Following the video surfacing, Galliano apologized, went to rehab, and, over the last few years, experienced a brand resurgence that some would call a whitewashing.
#mizrahi #bernhard #sense
28 days ago
Uefa has banned Fenerbahce midfielder Matteo Guendouzi for his team's opening two Champions League fixtures following a series of provocations and insults during a chaotic play-off victory away at Lyon last month.
The 27-year-old, previously a player for Lyon's major rivals Marseille, found himself at the centre of unrest before and after Fenerbahce's 2-1 win on 26 August, which included a mass brawl.
The victory secured the Turkish side a place in the Champions League for the first time in 18 years. Guendouzi, who previously made 82 appearances for ****** nal between 2018 and 2020, is set to sit out Fenerbahce's home encounter against Roma next Thursday alongside their trip to Aston Villa on 14 October.
He will be available for Fenerbahce's final six games in the league phase of the Champions League, starting with his side's match against Slavia Prague on 20 October.
Disciplinary verdicts released late on Friday detailed charges against Guendouzi for violating decent conduct rules, "insulting players or others present at the match" and provoking spectators.
#league #previously #uefa
The 27-year-old, previously a player for Lyon's major rivals Marseille, found himself at the centre of unrest before and after Fenerbahce's 2-1 win on 26 August, which included a mass brawl.
The victory secured the Turkish side a place in the Champions League for the first time in 18 years. Guendouzi, who previously made 82 appearances for ****** nal between 2018 and 2020, is set to sit out Fenerbahce's home encounter against Roma next Thursday alongside their trip to Aston Villa on 14 October.
He will be available for Fenerbahce's final six games in the league phase of the Champions League, starting with his side's match against Slavia Prague on 20 October.
Disciplinary verdicts released late on Friday detailed charges against Guendouzi for violating decent conduct rules, "insulting players or others present at the match" and provoking spectators.
#league #previously #uefa
28 days ago
Judge William F. Sullivan officially declared a mistrial in the weeks-long murder trial against Lindsay Clancy in Massachusetts on Sept. 4. Clancy's defense attorney, Kevin Reddington, had filed an emergency stay, but the state Supreme Court denied the appeal. The mistrial comes after the jury failed to reach a unanimous verdict after seven days of deliberations.
#judge #clancy #massachusetts #reddington
#judge #clancy #massachusetts #reddington
29 days ago
McLaren and Red Bull have won their appeals against the result of the Monaco Grand Prix after a controversy over multiple incorrect pit-lane speeding penalties.
The victory means Alpine's Pierre Gasly loses the podium he was awarded after an appeal by the French team that overturned two five-second penalties.
That means Gasly, who finished third on the road, is dropped back to the seventh place he received in the official results.
Red Bull's Isack Hadjar is returned to third place and McLaren's Oscar Piastri fourth, with Racing Bulls' Liam Lawson and Arvid Lindblad moving up to fifth and sixth.
However, the verdict does not fully address the multiple effects of a series of pit-lane speeding penalties.
#penalties #multiple #speeding #place
The victory means Alpine's Pierre Gasly loses the podium he was awarded after an appeal by the French team that overturned two five-second penalties.
That means Gasly, who finished third on the road, is dropped back to the seventh place he received in the official results.
Red Bull's Isack Hadjar is returned to third place and McLaren's Oscar Piastri fourth, with Racing Bulls' Liam Lawson and Arvid Lindblad moving up to fifth and sixth.
However, the verdict does not fully address the multiple effects of a series of pit-lane speeding penalties.
#penalties #multiple #speeding #place
29 days ago
Kris Boyd has delivered a brutal verdict on the £2.5m Rangers centre-back after a shaky display against Falkirk, arguing that his uncertainty spread through the Rangers defence during Wednesday's 2-1 Premiership win.
The Glasgow Times reported Boyd's comments, made during Sky Sports coverage, after Emmanuel Fernandez endured a difficult night despite his side taking all three points. Boyd focused on the opening half incident that led to Falkirk's equaliser. Fernandez followed an opponent too far, went down looking for a foul and left ******* e behind him. Ethan Ross then delivered the cross, with Kosta Nedeljkovic turning it into his own net.
Boyd saw little excuse for Fernandez's decision-making. He pointed to a loose square pass after the interval, when Jacob Murrell intercepted inside the penalty area before Ivor Pandur rescued Rangers with a save.
He said: "There's a tug, but I'd be more disappointed that my centre-back goes in and attempts to tackle like that.
"It summed up Emmanuel Fernandez's first half. He was really, really sloppy with the ball. You speak about good players making the people around them better — he's the opposite.
#really
The Glasgow Times reported Boyd's comments, made during Sky Sports coverage, after Emmanuel Fernandez endured a difficult night despite his side taking all three points. Boyd focused on the opening half incident that led to Falkirk's equaliser. Fernandez followed an opponent too far, went down looking for a foul and left ******* e behind him. Ethan Ross then delivered the cross, with Kosta Nedeljkovic turning it into his own net.
Boyd saw little excuse for Fernandez's decision-making. He pointed to a loose square pass after the interval, when Jacob Murrell intercepted inside the penalty area before Ivor Pandur rescued Rangers with a save.
He said: "There's a tug, but I'd be more disappointed that my centre-back goes in and attempts to tackle like that.
"It summed up Emmanuel Fernandez's first half. He was really, really sloppy with the ball. You speak about good players making the people around them better — he's the opposite.
#really
30 days ago
Amid all the noise surrounding Kawhi Leonard and the Los Angeles Clippers after the NBA's ruling, Shams Charania has revealed the status of his move to the Toronto Raptors.
The Los Angeles Clippers and Kawhi Leonard have been under NBA investigation for salary cap circumvention for nearly a year. The league announced its ruling on Wednesday and it's bad.
The franchise is facing severe punishments including forfeiture of first-round picks and bans for top executives. Leonard himself has gotten off relatively easy with a $700K fine.
Even before all this came out, Kawhi and the Clips had already agreed to move on, and a trade was agreed with the Toronto Raptors. Following the NBA's verdict, there is an update on that situation.
Photo by Ronald Martinez/Getty Images
#clippers #toronto #ruling #agreed
The Los Angeles Clippers and Kawhi Leonard have been under NBA investigation for salary cap circumvention for nearly a year. The league announced its ruling on Wednesday and it's bad.
The franchise is facing severe punishments including forfeiture of first-round picks and bans for top executives. Leonard himself has gotten off relatively easy with a $700K fine.
Even before all this came out, Kawhi and the Clips had already agreed to move on, and a trade was agreed with the Toronto Raptors. Following the NBA's verdict, there is an update on that situation.
Photo by Ronald Martinez/Getty Images
#clippers #toronto #ruling #agreed
30 days ago
Roma breathed a sigh of relief after the results of Evan Ndicka's medical tests.
The verdict ruled out any muscle injuries: it's merely inflammation. He won't be sidelined for long.
The Ivorian defender's presence against Atalanta remains in doubt, however, given that the match is scheduled for Saturday at 8:45 PM, in two days' time.
This won't be a problem for Gasperini, who has multiple options to fill in for the 1999-born defender.
Gian Piero Gasperini has several options to replace Evan Ndicka.
#evan #gasperini #options #atalanta
The verdict ruled out any muscle injuries: it's merely inflammation. He won't be sidelined for long.
The Ivorian defender's presence against Atalanta remains in doubt, however, given that the match is scheduled for Saturday at 8:45 PM, in two days' time.
This won't be a problem for Gasperini, who has multiple options to fill in for the 1999-born defender.
Gian Piero Gasperini has several options to replace Evan Ndicka.
#evan #gasperini #options #atalanta
30 days ago
On August 12, Royalty Pharma (NASDAQ:RPRX) agreed to pay Zealand Pharma $100 million for the rights to future royalties on rusfertide, an experimental treatment for a rare blood disorder called polycythemia vera. It is Royalty Pharma's second collaboration with Zealand, and it arrives just as rusfertide awaits a decision from the FDA. For a company that makes its living buying pieces of other companies' drugs, the timing says a lot about how it weighs risk against reward before a regulatory verdict even lands.
Royalty Pharma's business depends on picking the right moment to buy into a drug's future, and this deal fits that pattern. Under the agreement, $50 million changes hands at closing and the remaining $50 million arrives on the first anniversary, in exchange for a 1% royalty on rusfertide's global sales plus any regulatory and commercial milestones. Rusfertide, a once-weekly self-injected therapy that mimics the hormone hepcidin to control iron levels in polycythemia vera patients, already has an FDA goal date set for the third quarter of 2026, with Takeda lined up to handle commercialization worldwide. That is a near-term catalyst most royalty purchases do not carry.
The broader portfolio backs up the confidence. Royalty Receipts grew 14% to $768 million in the second quarter of 2026, lifted by Tremfya, Voranigo, Imdelltra and Evrysdi, and the company raised its full-year 2026 guidance for Portfolio Receipts to a range of $3.4 billion to $3.5 billion, the second increase this year. Capital deployment has already topped $1 billion in 2026, including a July 2026 royalty purchase tied to AstraZeneca's cliramitug, pushing the development-stage pipeline to 19 potential therapies. Even after repaying a $380 million term loan in July 2026, Royalty Pharma still paid a quarterly dividend of $0.235 per share and bought back $45 million of stock in the second quarter alone.
Not every royalty ages well, and Royalty Pharma's own numbers show it. Promacta royalties fell 75% in the second quarter of 2026 to just $8 million as US generic competition took hold, and Imbruvica payments slipped 16% to $36 million, a reminder that patent cliffs eventually catch up to even the steadiest cash flows. That same risk sits underneath every new deal the company signs, including the one with Zealand.
The rusfertide agreement carries its own strings. Royalty Pharma's 1% royalty stops scaling once global sales pass $1.5 billion, at which point Zealand keeps a 0.25% cut and Royalty Pharma only 0.75%, so the largest commercial outcomes get split rather than fully captured. And rusfertide still has not cleared the FDA. The agency's goal date only falls in the third quarter of 2026, meaning the second $50 million payment is committed before regulators finish their review. Layer that onto a balance sheet carrying $9.2 billion in total debt principal against $812 million of cash as of June 30, 2026, and it becomes clear this is a company funding new bets with borrowed as w
Royalty Pharma's business depends on picking the right moment to buy into a drug's future, and this deal fits that pattern. Under the agreement, $50 million changes hands at closing and the remaining $50 million arrives on the first anniversary, in exchange for a 1% royalty on rusfertide's global sales plus any regulatory and commercial milestones. Rusfertide, a once-weekly self-injected therapy that mimics the hormone hepcidin to control iron levels in polycythemia vera patients, already has an FDA goal date set for the third quarter of 2026, with Takeda lined up to handle commercialization worldwide. That is a near-term catalyst most royalty purchases do not carry.
The broader portfolio backs up the confidence. Royalty Receipts grew 14% to $768 million in the second quarter of 2026, lifted by Tremfya, Voranigo, Imdelltra and Evrysdi, and the company raised its full-year 2026 guidance for Portfolio Receipts to a range of $3.4 billion to $3.5 billion, the second increase this year. Capital deployment has already topped $1 billion in 2026, including a July 2026 royalty purchase tied to AstraZeneca's cliramitug, pushing the development-stage pipeline to 19 potential therapies. Even after repaying a $380 million term loan in July 2026, Royalty Pharma still paid a quarterly dividend of $0.235 per share and bought back $45 million of stock in the second quarter alone.
Not every royalty ages well, and Royalty Pharma's own numbers show it. Promacta royalties fell 75% in the second quarter of 2026 to just $8 million as US generic competition took hold, and Imbruvica payments slipped 16% to $36 million, a reminder that patent cliffs eventually catch up to even the steadiest cash flows. That same risk sits underneath every new deal the company signs, including the one with Zealand.
The rusfertide agreement carries its own strings. Royalty Pharma's 1% royalty stops scaling once global sales pass $1.5 billion, at which point Zealand keeps a 0.25% cut and Royalty Pharma only 0.75%, so the largest commercial outcomes get split rather than fully captured. And rusfertide still has not cleared the FDA. The agency's goal date only falls in the third quarter of 2026, meaning the second $50 million payment is committed before regulators finish their review. Layer that onto a balance sheet carrying $9.2 billion in total debt principal against $812 million of cash as of June 30, 2026, and it becomes clear this is a company funding new bets with borrowed as w
1 month ago
The Mavericks' minority owner, Mark Cuban, reacted to the NBA's recent verdict in the Kawhi Leonard salary-cap circumvention controversy with the Clippers.
"Congrats, Pablo," wrote Cuban on X.
NBA fans took to social media and saw the billionaire businessman's two-word response. They flooded the comment section with criticism, calling Cuban out for backtracking on his comments about Pablo Torre, the investigative journalist who first reported the story.
"Not sure how you thought they were innocent. This smelled like rotting fish from the beginning."
"Man…you were so wrong in this one. Always side with the smarter people…Pablo is much smarter than Ballmer. And Pablo actually works for a living."
#pablo #smarter #kawhi #torre
"Congrats, Pablo," wrote Cuban on X.
NBA fans took to social media and saw the billionaire businessman's two-word response. They flooded the comment section with criticism, calling Cuban out for backtracking on his comments about Pablo Torre, the investigative journalist who first reported the story.
"Not sure how you thought they were innocent. This smelled like rotting fish from the beginning."
"Man…you were so wrong in this one. Always side with the smarter people…Pablo is much smarter than Ballmer. And Pablo actually works for a living."
#pablo #smarter #kawhi #torre
1 month ago
The verdict is in regarding the Kawhi Leonard saga, and the results are not good for the All-Star forward or his soon-to-be former team.
A months-long independent investigation found the Los Angeles Clippers illegally circumvented the NBA salary cap when they facilitated outside endorsement deals with a collection of team-friendly sponsors, the league announced Wednesday.
Those sponsors were Aspiration Partners, Boingo Wireless, Daktronics and Lockton Insurance.
The resulting penalties are staggeringly stiff.
Due to what the league called a pattern of misconduct uncovered in the investigation, headed by the law firm of Wachtell, Lipton, Rosen & Katz, the NBA has suspended team owner Steve Ballmer from all league and team activities for a year. He has also been fined $30 million.
#sponsors
A months-long independent investigation found the Los Angeles Clippers illegally circumvented the NBA salary cap when they facilitated outside endorsement deals with a collection of team-friendly sponsors, the league announced Wednesday.
Those sponsors were Aspiration Partners, Boingo Wireless, Daktronics and Lockton Insurance.
The resulting penalties are staggeringly stiff.
Due to what the league called a pattern of misconduct uncovered in the investigation, headed by the law firm of Wachtell, Lipton, Rosen & Katz, the NBA has suspended team owner Steve Ballmer from all league and team activities for a year. He has also been fined $30 million.
#sponsors
1 month ago
Late Tupac Shakur's family expressed themselves recently following a guilty verdict that they have waited almost three decades to hear.
After the jury convicted Duane "Keffe D" Davis for the rap icon's 1996 fatal shooting, Tupac's family disclosed that they are both "elated and relieved" by the decision. However, the family made it clear that they do not see the verdict as the final chapter in Tupac's story.
The emotional statement comes one day after The Blast reported that members of the Shakur family were inside the Las Vegas courtroom when the verdict was announced. Now, the family is opening up about what the moment meant to them while also paying tribute to Tupac's late mother, Afeni Shakur.
The US Sun / MEGA
In a statement obtained by ABC News, one of Tupac's cousins, known as Aiysha Obafemi, who was at the court during the ruling, shared how the family reacted to the verdict.
#late #statement
After the jury convicted Duane "Keffe D" Davis for the rap icon's 1996 fatal shooting, Tupac's family disclosed that they are both "elated and relieved" by the decision. However, the family made it clear that they do not see the verdict as the final chapter in Tupac's story.
The emotional statement comes one day after The Blast reported that members of the Shakur family were inside the Las Vegas courtroom when the verdict was announced. Now, the family is opening up about what the moment meant to them while also paying tribute to Tupac's late mother, Afeni Shakur.
The US Sun / MEGA
In a statement obtained by ABC News, one of Tupac's cousins, known as Aiysha Obafemi, who was at the court during the ruling, shared how the family reacted to the verdict.
#late #statement
