Chris Boswell has officially etched his name in the Pittsburgh Steelers' history books during the team's Week 6 win over the Tampa Bay Buccaneers.
Trailing the Buccaneers 13-0, the Steelers called on Boswell to kick a 52-yard field goal, which he made with ease. This successful field goal was the 309th of his career and would tie legendary Steelers kicker Gary Anderson's record for the most field goals made in team history. Oh, but Boswell wasn't finished there, as he successfully connected on a 39-yard attempt to secure his 310th field goal, surpassing Anderson and setting a new record in Pittsburgh that should only grow this season. Boswell also hit on two more field goals to close out the game, pushing the record to 312.
The Wizard of Boz 🪄

📲 Stream on NFL+: https://t.co/vqIDzYZB2x pic.twitter.com/CtdPTQ6rt1
Boswell, who signed with the Steelers in 2015, wasted little time emerging as one of the league's top kickers, earning two Pro Bowl selections in 2017 and 2024, as well as First-Team All-Pro recognition in 2024.
The field goal record isn't the only feat Boswell was after, as the talented kicker is also 43 points away from breaking Gary Anderson's all-time scoring record of 1,343 points. We at Steelers Wire will be watching closely over the next several weeks as Boswell continues to remind fans why he's one of the greatest kickers ever to do it.

#boswell #record #pittsburgh #team

Fans question NFL's roughing-the-passer rules after controversial calls against Packers, Chiefs originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here.
Roughing-the-passer has always proved to be a sore subject for NFL fans. That fact resurfaced once more in Week 6.
Some might consider the penalty, ushered in to protect passers from sustaining major injuries, as a godsend. Others view it more negatively, believing it should be reformed to prevent honest defenders from coming under its wretched glare.
Regardless of where you stand on the debate, it's clear that many don't believe slight contact should come under its purview. Someone appeared to inform some of the NFL's referees, however.
Here's what you need to know.

#passer

McDonald's is facing a federal lawsuit that alleges its AI-enhanced pricing tool violates antitrust laws because it shares nonpublic data with franchisees who might be competing in the same market.
The lawsuit, which was filed Friday in Illinois, said McDonald's pricing tool uses artificial intelligence to collect data that competing franchises wouldn't normally share, like store-level sales. The Chicago-based burger giant has said it makes the tool available to U.S. franchisees to help them set prices at their individual restaurants.
The lawsuit also blames the pricing system for raising McDonald's U.S. prices.
"McDonald's has built and for years deployed its own information-sharing pricing platform, which draws on data from its millions of daily transactions to set menu prices across thousands of U.S. restaurants," the lawsuit states. "The result is algorithmic price-fixing aimed at customers who are already stretched thin."
McDonald's said Tuesday that the lawsuit is "filled with inaccuracies" and it would vigorously defend itself.

#restaurants

The Princess of Wales is always poised, elegant and professional during her royal engagements, and she kept her composure even when subtly asking the press to step backwards as she walked by amid an engagement in Norfolk.
It was in June 2020, when COVID-19 restrictions were still in place, that Kate, who was then the ***** ss of Cambridge, made her first face-to-face public engagement since lockdown began. The royal visited Fakenham Garden Centre near her country home, Anmer Hall, and she was seen holding her hands up to distance herself from the press amid the 'two-meter rule'.
Kate adhered to the two metre rule implemented by the UK government (@ Photo: Getty Images)
She could be heard saying: "Hello, how are you? This is two meters," as she moved slightly away from them and stretched out her hands. She then headed to greet employees of the centre, again at a safe distance.
During the visit, Kate shared that her children, Prince George, Princess Charlotte, and Prince Louis, all love visiting garden centres. She also highlighted their enthusiasm for gardening at home, revealing that George enjoys playing with Venus flytraps and that all three children were thrilled to grow tomato plants from seeds, and they grew as tall as the young royals themselves.

#prince #press

Boeing locked Korean Air into a $36.2 billion order spanning 737 MAX, 787-10, and 777X variants, but no deliveries arrive until the early 2030s.
Lockheed Martin posts steady profits while Boeing burns cash lifting production rates, carrying $600 million in quarterly interest expense that pressures GAAP results.
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Boeing (NYSE:BA) confirmed a firm Korean Air order for the stretched 737 MAX, 787-10, and 777X in passenger and freighter variants, valued at $36.2 billion. Deliveries begin in the early 2030s.
These aircraft were previously logged as unidentified orders from a commitment announced last summer, so this is existing backlog getting a customer name rather than fresh demand.

#boeing #deliveries

Whirlpool already cut its dividend 49% then skipped a payment entirely, while KHC's yield is inflated by a 55% decade-long price collapse with frozen payouts since 2019.
IEP's 29% yield masks two prior cuts and a 68% cash drop year over year, while UPS's quarterly operating cash flow fell $469 million short of its dividend payout.
A collapsing share price mechanically inflates yield, making high-yield stocks look attractive precisely when the underlying business is deteriorating most.
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Yield is a promise, not a payment. When a stock advertises a payout that looks two or three times the market average, it usually means the market has already decided something is wrong. The screen below flags six US-listed names where the numbers behind the yield show real strain: shrinking cash flow, stretched coverage, or a share price that collapsed and inflated the yield mechanically. None of these companies has announced a cut. Each has warning signs a retirement-focused reader should understand before buying the yield.

#inflated

During market uncertainty, cautious investors may feel compelled to sell everything while they wait for the dust to settle. But Ross Gerber believes that, to paraphrase Rudyard Kipling, if you can keep your head when everyone else is losing theirs, you'll reap even bigger rewards.
The Gerber Kawasaki CEO says that while inflation, higher bond yields, oil prices, and Federal Reserve rate hikes can pressure stocks, he does not think investors should abandon equities wholesale. Instead, he advocates for a more defensive approach.
He recommends investors trim holdings with valuations that look stretched relative to their growth, build reserves in cash and short-duration fixed income **** ets, and keep long-term positions in companies that he believes still have strong earnings support, such as Nvidia.
And for investors trying to navigate an environment where corporate earnings remain strong while macroeconomic risks pressure stock valuations, that distinction matters. Gerber's framework is less about calling the market's next move than deciding which risks a portfolio can absorb—and which positions still deserve capital.
Here is a closer look at Gerber's defensive-focused strategy.

#gerber #pressure #still

Micron (NASDAQ: MU) and Sandisk (NASDAQ: SNDK) have been two of the best-performing stocks in the S&P 500 (SNPINDEX: ^GSPC) so far this year. Sandisk is leading the way with an incredible 550% gain. Micron is in fourth place, up by over 220%. That means both of these stocks have tripled (or more than tripled in Sandisk's case), but I think that's just the beginning. In fact, if you invested $2,500 in each of these stocks, for a total of $5,000, I think that the combined value of those stakes will rise to $15,000 by the time 2028 arrives.
While that may sound far-fetched, the math backs it up, suggesting that these are two of the best investments you could make in the stock market right now.
Missed Nvidia in 2009? This Rare Signal Is Flashing Again. In 2009, a "Double Down" signal flashed for a little-known chipmaker called Nvidia. For the first time in years, that same "Total Conviction" signal is flashing for a company 1/100th the size of Nvidia. Continue »
The reason these two have done so well in 2026 is that there is no spare memory chip production capacity left. Micron and Sandisk are two of just three big players in this industry, and all of their production is being eaten up by massive demand for additional artificial intelligence computing power. AI processors and servers need heavy volumes of memory to function efficiently, and as a result, there's now a serious shortage of memory, so prices are skyrocketing.
This supply-and-demand imbalance is the culprit behind rising prices for consumer computing hardware, as these devices all require memory chips, too.

#NVIDIA #memory #flashing #best

AMD stock surged 127% YTD after Data Center revenue doubled to $6.7B, yet 24/7 Wall St. rates it HOLD at $481 on stretched valuation.
Nvidia trades at a P/E of 44 despite $89B in Data Center revenue, making AMD's triple-digit multiple look dangerously extended by comparison.
Lisa Su sees a $1.4 trillion AI accelerator market by 2030, with Helios delivering 30% more tokens per dollar than rivals.
Read More: Avoid these 13 retirement mistakes before they derail your future (sponsor)
Our AMD (NASDAQ:AMD) call is one of the tougher ones we've made this quarter. The stock has done what few thought possible, doubling in months on the back of an AI accelerator story that is finally landing with hyperscalers.

#revenue #hold #NVIDIA

Bob Mackie had strong feelings about Kim Kardashian wearing Marilyn Monroe's historic dress.
The legendary fashion designer, whose death was announced Sept. 14 at age 87, sketched the original design at the start of his career while working as an ***** istant to French-born costumer Jean Louis.
Monroe made American history in 1962 when she wore the nude shimmering gown during her performance of "Happy Birthday" for then-President John F. Kennedy. The dress and her serenade were never forgotten.
So much so that 60 years later in 2022, Kardashian worked with the owner of the dress, Ripley's Believe It or Not! museum, to wear the bling-encrusted gown to the Met Gala, acknowledging that she slimmed down dramatically to fit into it.
Mackie called Kardashian's wearing of the skin-tight gown a "big mistake," telling Entertainment Weekly that Monroe was "a goddess. A crazy goddess, but a goddess." He went on to describe her as "just fabulous," noting that the dress "was designed for her."

#dress

Broadcom's AI revenue surged 221% year over year with a forward P/E of 19, making it cheaper than Nvidia despite a similar growth trajectory.
TSMC revenue rose 53% year over year at a forward P/E of 20, and Dell booked a record $61B in AI orders last quarter.
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On a recent Earn Your Leisure episode, hosts Troy Millings and Rashaad Bilal split openly on where the next dollar of AI value accrues. Millings argued for names outside the Magnificent 7 and made Broadcom's custom accelerator business the centerpiece of the case. Bilal countered that "you have to go with the people who are on the leaderboard," naming Taiwan Semiconductor (NYSE:TSM), Nvidia (NASDAQ:NVDA), Micron (NASDAQ:MU), Apple (NASDAQ:AAPL), Alphabet (NASDAQ:GOOG, NASDAQ:GOOGL), Microsoft (NASDAQ:MSFT), and the Nasdaq 100.
I find Millings the more persuasive of the two. Broadcom (NASDAQ:AVGO) posted AI semiconductor revenue of $16.7 billion in the third quarter of fiscal 2026, up 221% year over year, and guided the fourth quarter to $21.7 billion, up 236%. On the earnings call, Hock Tan sketched a trajectory to roughly $115 billion in fiscal 2027 and $230 billion in fiscal 2028.

#NVIDIA #billion #enter

Ciena surged 5% Friday to erase its post-earnings selloff, with Arista Networks also gaining 5% as money rotated into networking equipment as a group.
IYW gained just 2% and SPY 1% while networking stocks surged 4-5%, confirming the move as a targeted sector rotation, not a broad tech rally.
Ciena's 10.7% weekly gain makes it the group's swing name, where the post-earnings gap is nearly filled and further upside requires fresh buyers or a new catalyst.
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Ciena (NYSE:CIEN) stock is up 5% to $351.38 in early Friday afternoon trading, extending a rebound that's now stretched across the full week. The move reverses the post-earnings selloff that followed Ciena's September 3 fiscal third quarter release. Today's advance has effectively closed the door on the initial negative reaction to the report and pushed the stock back through the level it held before the release.

#Stock #Friday

Former Australia opener David Warner found himself in a playful social media exchange with England's famous fan group, the Barmy Army, on Friday, and the banter quickly moved from Saim Ayub's ducks to Marnus Labuschagne's century drought, England's curfew troubles and Warner's long-running Stuart Broad problem.

It all started when the Barmy Army took a dig at Warner after Pakistan batter Saim Ayub registered a pair of ducks in the final Test against England at Edgbaston. The England fan group posted a statistic pointing out that Ayub had now registered a pair twice on English soil.
Replying to the Barmy Army, Warner wrote: "Interesting stat. When was the last time I went 42 innings without a Test hundred??"
The reference was not actually about Warner. The 42 innings was a cheeky dig at former Australia teammate Marnus Labuschagne, who had gone through a lengthy drought without a Test century. Labuschagne's last Test hundred came against England at Headingley in 2023, and his drought had stretched to 42 innings.

But he wasn't finished. Then came the curfew dig.

Warner followed his 42-innings reference with another jab: "Oh do you guys still have a curfew? Asking for a mate."

That was a reference to England's recent off-field disciplinary issues involving players breaking team curfew and going out drinking. The issue had become a talking point around the England setup, with fast bowler Brydon Carse among the players caught up in the recent controversy.

#australia

Natasha Poly attended the Be Brave premiere during the Venice Film Festival on Thursday, joined on the red carpet by Diesel creative director Glenn Martens.
SGP Stefano Guindani Photo
The model wore a custom Diesel gown that took one of the most basic pieces in any wardrobe – the white tank top – and stretched the idea all the way to the Venice red carpet.
SGP Stefano Guindani Photo
Made from ribbed jersey, the fitted tank construction extended into a floor-length silhouette with draping through the skirt and an enormous train. And enormous really is the word here. At one point, it required ******* istance just to make its way along the red carpet.

#carpet #stefano

Sept. 11 (UPI) -- Ready or not, here it comes: The official "Road to the Kentucky Derby" series starts Saturday with the $300,000 Grade III Iroquois Stakes at -- where else? -- Churchill Downs.
And -- who else? -- six-time Derby winner Bob Baffert trains the 8-5 favorite, Salahudin.
Salahudin, an Uncle Mo colt, won his first start by 2 lengths July 17 at Ellis Park going 6 1/2 furlongs. He stretched out to 7 furlongs in the Ellis Park Juvenile on Aug. 9 and won that by 4 1/2 lengths.
The 1-mile Iroquois Stakes has nine entries. Blessed Flyer also is 2-for-2 and won the Bashford Manor at Churchill Downs June 28 for trainer Mike Tomlinson. He Is No Lie finished second in the Bashford Manor, and then was fourth in the Grade III Best Pal at Del Mar. The others are maiden winners.
Also on the weekend agenda are five Breeders' Cup "Win and You're In" races in North America and five more in Ireland.

#park

Yankees news: Anthony Volpe gets brutally honest on 'whirlwind' of getting back to majors appeared first on ClutchPoints. Add ClutchPoints as a Preferred Source by clicking here.
Anthony Volpe did not have a quiet return to the big leagues. He made it as loud as he could, and he did it with his bat during Thursday's series finale against the Colorado Rockies at Yankee Stadium in the Bronx.
In his first game back to the majors, Volpe went 3-for-5 with five RBIs. His grand slam in the seventh inning further buried the Rockies, as it stretched New York's lead to eight runs, 10-2. The Yankees ultimately won the game to the tune of a 10-3 score.
"Unexpected whirlwind," the 25-year-old Volpe said following the game, describing what the past 24 hours had been for him (h/t Gary Phillips of NY Daily News Sports).
Watch sports LIVE with fuboTV (free trial)

#game #anthony #sports

A federal court on Sept. 9 dismissed a lawsuit between former Memphis football receiver Cortez Braham and the NCAA, ending a legal saga that stretched on for more than a year.
Braham initially sued the NCAA in 2025 to get an additional year of eligibility. He was granted a preliminary injunction before transferring to Memphis, where he was the Tigers' leading receiver in 2025. After the season ended, Braham's lawyers filed a motion to dismiss the lawsuit.
The NCAA fought it, saying in legal filings that it wanted to enforce the "rule of restitution" against Memphis for playing a player they said should have been ineligible. Lawyers for both sides argued their cases in a Las Vegas courtroom in March.
A ruling finally came on Sept. 9, when the panel of judges ruled that the case was moot and dismissed it.
"Famously, in sports, "it ain't over 'til it's over." But, in this case, it's over," Judge Gabriel P. Sanchez wrote. "The game clock has run out on the 2025 college football season. With these appeals, the NCAA attempts one last Hail Mary pass: asking us to reverse the preliminary injunctions granted to these college football players that allowed them to play in the now complete 2025 season. Because these injunctions have already expired and these players' collegiate careers are over, no effective relief can be granted to the NCAA. We therefore dismiss these appeals as moot."

#granted #season #braham #lawyers

Cooper Kupp made the play of the game Wednesday night, pulling in an impressive one-handed catch during the third quarter of the Seattle Seahawks' season-opening win over the New England Patriots.
Seattle was trailing 10-0 when quarterback Drew Lock threw toward Kupp along the right sideline. Kupp tracked the pass, adjusted his position and stretched out with one hand to make the big reception. The grab gave the Seahawks a critical spark as they attempted to overcome the early deficit.
Kupp appeared to add a touchdown later in the game, catching a 7-yard pass in the end zone. However, the score was negated by a penalty, forcing Seattle to settle for a field goal and narrowing New England's advantage to 10-3.
The spectacular reception quickly became the game's defining highlight, showcasing Kupp's incredible athletic ability on the play while providing Seattle with momentum during its third-quarter comeback. The Seahawks went on to win the game by a score of 13-10.
This article originally appeared on Seahawks Wire: Seahawks vs. Patriots highlight of game: Cooper Kupp's one-handed grab

#seahawks #Seattle #game

Pamela Anderson brought a serious dose of color to Venice with her latest red carpet appearance. The actress stepped out for the amfAR Gala Venezia 2026 during the Venice Film Festival, trading understated neutrals for a striking orange look. Anderson commanded attention in the vibrant dress held up by thin strings, along with a pared-back beauty aesthetic that has become a signature of her recent appearances.
Pamela Anderson wore a custom Calvin Klein creation crafted from glossy orange satin. The floor-length dress featured an ultra-minimalist neckline held in place by two incredibly thin spaghetti straps, which stretched over her shoulders and left her bust completely exposed. With barely any fabric supporting the top, the delicate straps became one of the riskiest details of the elegant silhouette.
The gown featured a straight-across neckline and fitted bodice before falling into a long, fluid skirt. Its satin construction caught the light from every angle, making the fiery orange shade appear even more intense on the carpet. Subtle seams through the bodice gave the streamlined dress structure.
Anderson added another dramatic element with a coordinating oversized satin wrap. Rather than wearing it traditionally, she allowed the voluminous piece to fall loosely from her shoulders and arms. The extra fabric cascaded down both sides of her body before pooling behind her. This created the effect of a sweeping train and added more volume to the dress.
She kept everything else simple. Anderson wore her blonde hair in soft, shoulder-length waves with a side part and appeared to embrace a minimal beauty approach. Small earrings provided a subtle finishing touch without competing with the vivid gown.

#pamela #venice #carpet

This Tuesday, the 30 nominees for the 2026 Ballon d'Or will be revealed.
And on Monday evening, some journalists started sharing a few insider tidbits. The most WTF of them: the presence of Sadio Mané and Julián Quiñones among the 30 nominees, as reported by independent journalist SamC_reports.
Pretty far-fetched stuff...
On Monday evening in Spain, Getafe were held to a 1-1 draw by Celta Vigo on matchday four of La Liga.
But the match was mainly marked by the incredible record achieved by Getafe goalkeeper David Soria.

#Monday

Florida State spent much of Monday night chasing the game, but after battling back to tie SMU in the fourth quarter, the Seminoles could not find one final stop or scoring drive.
In a game delayed by a power outage at Doak Campbell Stadium and stretched deep into the night, FSU showed more resilience than it did in its season opener. However, the same issues that have plagued the Seminoles through two games, inconsistent quarterback play, offensive line struggles and third-down defensive lapses, resurfaced in a 27-24 loss to SMU.
The Seminoles dropped to 1-1 on the season despite erasing multiple deficits and tying the game at 24 before the Mustangs answered with the decisive touchdown drive.
Here are the grades from Florida State's loss to SMU.
Daniels spent much of the night under constant pressure and rarely looked comfortable in the pocket. While there were flashes of playmaking ability, including a quarterback keeper for a touchdown and several throws into tight coverage, consistency remained an issue.

#seminoles

Deuce Alexander showed off his speed with a 62-yard catch-and-run for a touchdown in the third quarter of Mississippi's season opener against Louisville.
That score may have cost the Rebels some depth at wide receiver.
Shortly after the touchdown drive ended at Nissan Stadium in Nashville, Alexander was seen being stretched out on the sideline by members of the Rebels' medical staff. He eventually left for the locker room at the stadium for further evaluation.
Ole Miss vs Louisville live updates: Week 1 game score, highlights from Nashville
The Rebels are currently tied with the Cardinals 24-24 after Louisville responded to Alexander's 62-yard touchdown catch with a 62-yard touchdown pass from Lincoln Kienholz to Tre Richardson.

#nashville #stadium #score

8
Manchester United were held to a 2-2 draw by Everton at the Hill ****** inson Stadium. Here are our player ratings from the game.
(A score of 6 is around average.)
Senne Lammens 4 – He looked hesitant in a few big moments and really should have done better with Everton's equaliser. It just wasn't good enough from him.
Diogo Dalot 5 – Consistently stretched United's attack and took up advanced positions, eager to make an impact in the final third. Yet he was given a stern test by George, a battle that continued unabated when Jack Grealish entered the fray

#manchester #everton #stadium

LSU has not even played its first game under Lane Kiffin, and the Tigers have already reached the stage where their own conference is suing them.
The SEC filed a federal lawsuit Thursday seeking to stop LSU from using former NFL players, only for a Louisiana judge hours later to grant a preliminary injunction clearing a path for Dae'Quan Wright and Zxavian Harris to return to college football. Kiffin has defended pursuing the players, and the rest of the league is not exactly enjoying the show.
The anger has stretched beyond whether Wright and Harris should be eligible. For some SEC fans, LSU's willingness to fight the conference has become the bigger problem.
PREDICT THE CFB SEASON: PFN's Free CFB Playoff Predictor
"LSU Is Becoming a Pariah,"one fan wrote.

#harris

VC investment in quantum computing notched a record $2 billion in Q2 across 23 deals, accounting for a third of dollars in the chips and datacenters vertical, according to a new PitchBook report.
Quantum's marquee event this quarter was Quantinuum's IPO, which accounted for most of the $19 billion in quantum exit value and was the first major test of the technology in public markets. On the VC side, Oxford Quantum Circuits raised a £260 million Series C led by Bullhound Capital.
Strategics are eyeing quantum technologies, too. Miraex, a quantum hardware startup, was bought in June following Quantum Circuits $538 million sale earlier this year.
Overall, investment in chips and datacenters fell for the second consecutive quarter, hitting $6.6 billion across 133 deals in Q2. Despite the pullback from recent highs, 2026 is still on pace to exceed 2025's record of $21.6 billion.
The declines were concentrated in semiconductor chip design startups, which posted their weakest quarter since Q1 2025 at $1.7 billion. While newer chip design entrants like Etched, d-Matrix, and Ricursive Intelligence are making waves, the dominance of larger players has given investors pause.

#investment #across #deals #datacenters

If your crystal ball is looking a little murky, don't worry, you're not alone.
With more teams, a broken ******* le run and contrasting approaches to investment, this could be the most uncertain season of the Women's Super League yet. We could even see its power dynamics majorly disrupted for the first time in years.
London City Lionesses finished sixth last season but have signed two-time Ballon d'Or winner Alexia Putellas, signalling a shift in the league's status quo. Manchester United are entering a new era, with former Hearts head coach Eva Olid replacing Marc Skinner, whose five-year tenure ended in August. Does their focus on youth mean a place in the top four is up for the taking? Who will be the kingmakers in a ******* le race that feels more open now that Manchester City have ended Chelsea's run of six consecutive WSL ******* les? And who will emerge as the next England star as the women's game gears up for the 2027 World Cup?
Welcome to The Athletic's mega preview of the new Women's Super League season.
Manchester City lifted the WSL trophy for the first time in a decade, ending a once-impenetrable Chelsea dynasty that had stretched for a record six seasons.

#manchester

On August 26, Biohaven (NYSE:BHVN) and SK Biopharmaceuticals announced a global licensing agreement covering opakalim, Biohaven's lead epilepsy candidate, in a deal worth up to $795 million plus royalties. SK Biopharmaceuticals picks up exclusive worldwide rights to Biohaven's Kv7 ion channel platform, while Biohaven walks away with $400 million in near-term cash. The timing lines up with an August 10, 2026 earnings report that showed Biohaven still losing well over $100 million a quarter, and the gap between those two dates explains a lot about why this deal happened now.
SK Biopharmaceuticals will pay up to $795 million in upfront and milestone payments connected to the Kv7 platform, on top of tiered royalties on US net sales of opakalim that range from the mid-teens to low twenties. Biohaven collects $350 million at closing and another $50 million in 2027, with as much as $150 million more available through development and regulatory milestones plus royalties on global sales. SK Biopharmaceuticals is also taking over Kv7 program costs going forward, including certain Knopp Biosciences obligations. CEO Vlad Coric described the structure as proof Biohaven can monetize its pipeline through partnerships rather than leaning on public markets for cash.
The deal only makes sense because opakalim looks like it works. In a proof-of-concept study in idiopathic generalized epilepsy, the median time to a second generalized tonic-clonic seizure stretched to 141 days on opakalim versus 47 days on placebo, and a third of patients made it through the full 24 weeks without a second seizure. In focal epilepsy, 54% of patients in an open-label extension study saw at least a 50% drop in seizure frequency over any six months, in a group of more than 100 patients.
Opakalim is also designed as a once-daily pill with no ******* ration required, a real edge over older antiseizure drugs. Pairing that data with SK Biopharmaceuticals, the company behind XCOPRI and the only firm to bring a new focal-seizure drug to the US market since 2016, gives Opakalim a commercial path Biohaven would have struggled to build alone. The cash also buys runway for the rest of the pipeline, including protein degraders BHV-1300 and BHV-1400, which have shown rapid, selective reductions in disease-driving antibodies in Graves' disease and IgA nephropathy with clean safety data across nearly 200 patients dosed.
Biohaven is giving up full ownership of an ******* et it now believes could be a major seller. Royalties in the mid-teens to low twenties are real money, but they are a fraction of what outright ownership of an approved epilepsy drug would be worth, and $50 million of the $400 million upfront does not arrive until 2027. The Knopp Biosciences obligations SK Biopharmaceuticals is absorbing, worth up to $245 million plus mid-single-digit royalties, are a reminder that other parties already have claims on opakalim's future revenue before Biohaven sees a dollar of profit from it.

#ro

Originally appeared on E! Online
The way Isla Fisher sees it, a man doesn't have nine lives before she loses interest.
Over two years after announcing her split from Sacha Baron Cohen, the Now You See Me actress gave an update on her dating life, sharing one turnoff she experienced that made her cut a man off before he could run away with her heart.
"I have a dating ick that happened recently," Fisher said during a sitdown with Overheard Happy Hour shared Aug. 30. "I liked somebody. His dog ran away and he chased his dog. But instead of chasing upright, he ran low with his hands outstretched—like a cartoon."
And the 50-year-old wasn't feline fine as she watched the man's unconventional dog-snatching attempt. In fact, she became pawsitive she was out, adding, "The ick was growing and growing and by the time he caught the dog, he had lost the p---y."

#growing

The Los Angeles Clippers finally got an answer on the NBA's cap circumvention investigation, but it's not the one they were hoping for. Despite claiming innocence and complying with the league throughout the process, NBA Commissioner Adam Silver came down with strict penalties, including a $30 million fine, the loss of five draft picks, and suspensions for several Clippers executives.
Instead of accepting their losses, however, the Clippers plan to fight with everything they have. After making their initial statement today, they shared their official email to the Commissioner, in which they called him out on the way this investigation was conducted. According to the Clippers, they worked tirelessly to comply with the league office, committing millions of dollars and many hours to prove their innocence.
"Almost one year ago today, you announced that the league would be investigating podcast allegations that the Los Angeles Clippers engaged in salary cap circumvention by funneling money to Kawhi Leonard through a 'no-show' contract with a Clippers sponsor, Aspiration. In announcing that investigation, you represented that 'due process' and 'a fundamental sense of fairness' would govern the process. You made clear that the 'burden [would be] on the league' to prove any violation through actual evidence, not 'mere appearances.' And you concluded by promising that everyone involved in the investigation would be treated 'the same way I would want to be treated if people were making allegations against me.'"
"Unfortunately, none of those promises have been kept. In the last year, Steve Ballmer has spent nearly $50 million funding an investigation by Wachtell, Lipton, Rosen & Katz that has stretched far beyond the bounds of what the league set out to investigate, let alone the bounds of 'fundamental fairness.' The Clippers have produced more than 30,000 documents and provided more than 20 witnesses who have sat for 30 interviews."
"Third parties, including Clippers business partners and sponsors, have likewise provided documents, interviews, and statements to investigators. Mr. Ballmer has reimbursed the costs of at least six law firms, many of which were hired at the demand of the league's lawyers. To say the investigation has been a distraction would be an understatement—Clippers employees have spent thousands of hours scouring document repositories, phones, messaging systems, central files, and accounting records, working with counsel, and sitting for interviews. This investigation has permanently strained relationships with key Clippers stakeholders."

#angeles #commissioner #circumvention #innocence

WASHINGTON (AP) — President Donald Trump said Tuesday that he is nominating acting Navy Secretary Hung Cao for the permanent job, giving the Navy combat veteran the nod as concerns have emerged that some sailors have been stretched to the limit during the Iran war.
Cao has been serving as acting Navy secretary since John Phelan departed the job unexpectedly and without explanation in late April. Unlike Phelan, who had not served in the military or had a civilian leadership role in the service, Cao spent 25 years in the Navy as a special operations officer and went on to serve with SEAL teams and special forces in Iraq and Afghanistan.
"I am pleased to nominate a true WARRIOR," Trump wrote on social media, prodding the Senate "to confirm this Warfighter, ASAP."
Cao on social media called it the "honor of a lifetime to lead the great warriors of the Navy and Marine Corps team."
Cao's nomination comes as some, including Democrats in Congress, believe Trump has been overtaxing the Navy. The USS Abraham Lincoln aircraft carrier's nine-month deployment to support the Iran war has included a record-setting uninterrupted time at sea.

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