WATERBURY - Holy Cross High football senior star wide receiver Dae'Sean Graves will need to wait at least one more week to claim his second state record of the season.
Graves caught five passes for 113 yards, including a 46-yard touchdown, in Holy Cross' 56-8 win over WCA on Thursday night at Ray Snyder Sr. Field. The Crusaders improved to 6-1 with their sixth straight win, while the Spartans fell to 1-6.
Graves' touchdown added to his state record. He has 52 touchdown receptions for his career. The UConn commit tied and broke Southington great Alex Jamele's career record for touchdown receptions last week in a 52-13 win at Crosby.
Graves needs five more catches at Woodland on Friday, Nov. 6 (6:30 p.m.) to tie East Catholic great Joey Montalvo's career receptions record of 226. Six catches will give Graves the state record. He didn't play in the second half of Thursday's game.
Graves will need several more games to break Montalvo's career receiving-yards record of 3,871. He is 529 yards away from tying the mark.

#Career #state

Liverpool's midfield is probably going to be their main area of focus in the January transfer window.
At the moment, the Anfield outfit only have four central midfielders among their ranks with one of them being 19-year-old Trey Nyoni.
And, although each player is good, this season, only Alexis Mac Allister has really met expectations.
Indeed, Nyoni has done well when called upon but, since he's still so young, he can't be relied upon for every game.
Others, such as Dominik Szoboszlai and Ryan Gravenberch have failed to make their mark which is why so many midfielders have been linked with a Liverpool switch.

#nyoni #midfielders

The overall performance certainly wasn't perfect, but the Green Bay Packers still rolled to a two-score win over the visiting Dallas Cowboys on "Sunday Night Football" from Lambeau Field in Week 6. Brian Schottenheimer's team was well-rested after playing on Thursday night in Week 5 and not lacking motivation after a humbling home defeat in primetime, but the Packers still raced out to a 17-0 lead and ended up leading the game by two scores for most of the night. Matt LaFleur's team has won three straight games and is 4-2 overall, an acceptable record given the ups and downs of the early season.
Three big things from the Packers' win over the Cowboys:
Facing Dak Prescott, Javonte Williams, CeeDee Lamb and George Pickens without Micah Parsons, Edgerrin Cooper and Javon Hargrave provided a big test for Jonathan Gannon's defense, and the group passed it with flying colors. The Cowboys managed only 13 points, of which seven came in garbage time, and Gannon continually had Prescott under pressure and making rushed and confused decisions against the blitz or the pre-snap appearance of a blitz. Prescott averaged only 4.8 yards per attempt, and the Packers got a pair of interceptions inside their own 30-yard line and a pair of fourth down stops on pass attempts in the fourth quarter. More and more, the home opener disaster against the Atlanta Falcons is looking like a blip on the radar. The Packers have allowed fewer than 14 points in three straight games since.
The Packers offensive line took several steps forward in games against the Tampa Bay Buccaneers and Chicago Bears, largely due to the settling of performances at both guard spots. But Sunday night represented a step in the wrong direction and provided evidence that the problems along the offensive line aren't solved quite yet. Jordan Love was under pressure on 45.5 percent of his pass attempts, his highest percentage since Week 1. And the run game accomplished next to nothing, averaging only 2.2 yards per attempt overall and 1.8 yards on runs by Pierre Strong Jr., MarShawn Lloyd and Kaleb Johnson. The Packers got by because Love was excellent under pressure early, and the defense made enough stops so that the struggles moving the ball in the second half didn't matter. The inconsistency of the offensive line, drops in big spots and untimely penalties still look like the Packers' biggest hurdles.
Rookie kicker Trey Smack calmed fears of any prolonged struggles by making all five of his kicks, including all three field goals. Even on a breezy night inside Lambeau Field, Smack enjoyed a bounce-back performance -- even if only one of his five kicks was from over 40 yards (a 44-yard field goal). More importantly, Smack didn't let last week's issues bleed into a new opportunity. Against the Bears, his three misses cost the Packers seven points. On Sunday night, Smack's five converted kicks created 11 points in a 10-point win.

#field

It's been an extremely busy period for Earl Charles Spencer, the brother of the late Princess Diana, who has been non-stop in promoting his very personal book, Swan Song: Diana, My Sister. Following his time stateside to talk about the publication, he is back at his beloved Althorp estate and he's shared a poignant photo from the place where his sister is buried.
The Earl took to his personal Instagram Stories to share an image that he took during a moment of quiet contemplation from the edge of the Round Oval Lake, partially showing the central island where Diana is laid to rest. Pleased with his photography skills, Charles captioned the picture: "My luckiest capture of the Round Oval Lake, Althorp." The striking photo showed the sun piercing through the scattered clouds on a crisp autumn day as the mist hung around the base of the trees.
The lake where Diana is buried
Diana's final resting place was decided upon by Charles himself, following her tragic 1997 death. Originally, it was planned that she would be laid to rest in the Spencer family vault at the local church but security concerns ruled that out. Instead, the island on the lake was chosen and the bridge removed to restrict access even further. Now, family members paying their respects have to board a small boat to get to her exact gravesite.
A temple near the lake allows visitors to leave tributes for Princess Diana (@ Instagram)

#diana #oval

Joe Burrow is continuing his evolution from NFL quarterback to one of professional football's most closely watched dressers.
The Cincinnati Bengals star fronts Alo's latest fall campaign, introducing Java Brown to the lifestyle brand's seasonal color palette. The warm neutral appears alongside Gravel and Ivory across a selection of performance pieces, knitwear, tailoring and accessories.
In the campaign, Burrow models studio-to-street looks intended to move between training, travel and time away from the field. Featured pieces include the Alo Suited Trouser, Alpha Shell Long Coat and Cotton Ribbed Parallel Sweater. The Alo Voyage Duffle, an accessory that has previously appeared in Burrow's game-day arrivals, also returns.
The campaign builds on Burrow's ongoing relationship with Alo, which encompasses fashion, athletic performance and recovery. He previously appeared in the brand's Conquer Collection campaign and helped introduce its Alo Runner performance shoe.
"I've always been drawn to pieces that feel refined but effortless," Burrow said in a statement.

#burrow #campaign #appeared

"I want to be alone." The despairing words spoken by Greta Garbo while being spied on by a thief in her 1932 film Grand Hotel, have been injected with chilling new irony. Using the latest AI technique, the starlet has been brought back to life to flog ball bearings in an advert by the industrial Swedish Company SKF. And what a terrifying spectacle it makes.
The lifelike precision is terrific, from the smoky, undulating voice to the thin pencilled eyebrows that twitch between anxiety and hauteur.
At the same time there is something deathly about the figment. What made Garbo so brilliant to watch was that you didn't know where the woman started and the character began; when the camera was rolling she didn't so much perform as emerge. Her AI rendition has magnetism without presence.
True, the animation deploys cutting-edge AI techniques to evade successfully what is known as the "uncanny valley" trap, the nausea that people feel when faced with simulations that nearly – but do not quite – resemble real humans. But simulations like Greta's arguably occupy a new ******* e that one might call the "immaculate void".
Garbo's family gave their permission for the ad. But it's impossible to know how Garbo herself would have felt about it. As we extract commercial value from the departed without their consent, it begs the question: are we any better than Egyptian grave robbers, who sacrilegiously plundered the dead?

#greta #grand

Gov. Abbott says Texas data centers "dug their own grave" by expanding too fast, with fewer than 10% responding to a state electricity demand survey.
Claiming Social Security at 63 instead of 67 permanently locks in just 75% of the full benefit, costing a $2,500 earner roughly $625 monthly.
A long-term ground lease can bridge the income gap to delay Social Security claiming, and passive rental income generally avoids the Social Security earnings test.
Two retirees, same $1 million, same 4% rule, buy one finished with $1.4 million, the other hit $0 in 12 years. Our free reader guide explains the flaw that separated them, and the income-first method built to avoid it.
Texas spent years courting the data-center boom. Now Gov. Greg Abbott says the industry "dug their own grave" by expanding too quickly without winning over the communities expected to host the projects. The backlash is real.

#texas #grave

WASHINGTON (AP) — The top Democrat on the House Foreign Affairs Committee said Wednesday that he's going to block a proposed sale of $2.8 billion in heavy weaponry to Israel over concerns that the powerful bombs may not be used in line with U.S. and international law.
Rep. Gregory Meeks of New York said he would withhold approval for the sale because of "grave, unresolved concerns" about how these munitions could be used in densely populated areas of Gaza and Lebanon by Israeli Prime Minister Benjamin Netanyahu's government.
"The Trump administration has not provided sufficient ****** urances that these weapons will be used by the Netanyahu government in accordance with U.S. law and with appropriate protections for civilians," Meeks said in a statement. "I therefore will not clear this sale at this time."
Meeks' objections, however, will not likely affect the sale, which was informally notified to lawmakers on Tuesday. Once it is formally notified to Congress, Secretary of State Marco Rubio can bypass the normal congressional review process by making an emergency determination that the transaction is an urgent national security interest.
Rubio has done so in the past, including bypassing a normal congressional review process to approve a nearly $3 billion sale to Israel last year. The administration then approved a new series of arms sales to Israel totaling $6.67 billion in January.

#used

Billionaire Ray Dalio's Bridgewater **** ociates has disclosed several new picks in its Q2 filings. In this article, we are going to focus on two non-AI stocks in which the fund opened new stakes in the June quarter.
Vulcan Materials Company (NYSE:VMC) is the larger of the two. Bridgewater bought about 108,700 shares worth roughly $32.1 million, a 0.13% portfolio weight. Toy company Hasbro, Inc. (NASDAQ:HAS) was another notable new pick as the fund bought a stake worth about $20.8 million in the company.
Let's focus on VMC in this article and see whether the stock is a decent buy-the-dip opportunity. It's down about 14% so far this year.
Vulcan Materials is a major producer of construction aggregates in the US. Aggregates are crushed stone, sand and gravel, the base material under roads, bridges, foundations and parking lots. Demand for these materials comes from public infrastructure, private non-residential and residential projects.
The bull case

#bridgewater #vulcan

Fourteen years ago, Ken Jouppi, who had operated a charter airplane business in Alaska since the 1970s, agreed to fly a passenger from Fairbanks to Beaver, one of the state's dry jurisdictions. The passenger's luggage included 72 cans of Budweiser and Bud Light, which she planned to share with her husband on his birthday. Although most of the beer was boxed, a six-pack "was packed only in a grocery bag and would have been in plain view to Jouppi as he was loading the airplane," the Alaska Supreme Court noted last year.
State troopers discovered the beer before the plane took off, and Jouppi was convicted of a misdemeanor. The trial court, which concluded that Jouppi had been "willfully blind" to the six-pack, sentenced him to three days in jail and a $1,500 fine. But state law mandated another punishment that was 63 times as severe: forfeiture of Jouppi's $95,000 airplane. Although that penalty seemed grossly disproportionate, the Alaska Supreme Court ruled that it did not violate the Eighth Amendment's ban on excessive fines.
In July, responding to a petition filed by the Institute for Justice, the U.S. Supreme Court agreed to review that decision. It will hear oral argument in Jouppi v. Alaska on December 1. In a brief supporting Jouppi's appeal that it filed last week, the Cato Institute argues that the Alaska Supreme Court erred by failing to consider the gravity of his conduct and the financial consequences of the forfeiture. Both of those factors, Cato attorney Matthew Cavedon says, have been central to the common-law understanding of excessive fines for eight centuries.
"The Eighth Amendment was designed to prevent this kind of abuse by limiting excessive fines," Cavedon writes. "Long before the United States was founded, the common law protected people from extreme monetary penalties. But the Alaska Supreme Court's view is that challenges to excessive fines 'should rarely succeed.' This dismissive view led it to conclude that there is nothing excessive about the forfeiture of an airplane worth 'only 9.5 times the maximum fine'—and over 60 times the fine actually imposed. The decision below cannot be reconciled with this Court's precedent or the Excessive Fines Clause's original meaning."
In weighing the proportionality of the airplane forfeiture, the Alaska Supreme Court thought the relevant consideration was the harm caused by excessive drinking. "Alcohol abuse in rural Alaska leads to increased crime; disorders, such as alcoholism; conditions, such as fetal alcohol spectrum disorder; and death, imposing substantial costs on public health and the administration of justice," Justice Jude Pate wrote in the majority opinion. "Within this context, it is clear that the illegal importation of even a six-pack of beer causes grave societal harm."

#court #excessive #jouppi

A prisoner's premature baby died in hospital a day after he was born by emergency Caesarean section, an inquest has heard.
Orion Homer was born at 01:06 on 15 October 2023 at Royal Derby Hospital at 34 weeks plus five days gestation and died the following day.
An inquest at Derby Coroner's Court heard his mother Ellen Roberts was a prisoner at HMP Foston Hall and was taken to the hospital on 14 October after she raised concerns about reduced foetal movement.
Orion was "gravely unwell and very pale" when he was born and needed CPR and breathing support, the inquest heard.
Roberts had spent some of her pregnancy in prison in June and July 2023, before she was released at the end of July but recalled back on 10 October, the jury inquest heard.

#heard #roberts #july

Stellantis N.V. (NYSE:STLA)'s long-idled Belvidere ******* embly Plant in Illinois has been a case study for how a plant reopening can be pushed further into the future. The plant has been dormant since February 2023, when Stellantis N.V. (NYSE:STLA) ended the Jeep Cherokee production and laid off over 1,300 employees. A 2027 production target for Belvidere has now shifted, with Stellantis targeting pilot production of the next-generation Cherokee in the first half of 2028 and retail production in the second half of 2029, even as Stellantis portrays the news as a larger investment rather than a delay.
Stellantis N.V. (NYSE:STLA) announced an increase in its Belvidere investment to more than $800 million, up from a previous commitment of $600 million or more, and confirmed that the plant will produce the next-generation Jeep Cherokee on its new STLA One platform, the first vehicle built in the US on that modular design, which the company claims will improve manufacturing efficiency and reduce costs.
However, according to UAW Local 1268 president Matt Frantzen, citing internal records and talks with company executives, the updated schedule pushes pilot production into the first half of 2028, while retail production is not targeted to begin until the second half of 2029, roughly two years later than Stellantis' previous 2027 initial-production target.
The Belvidere news is a grave situation developing north of the border. Unifor, the Canadian union that represents Detroit Three autoworkers, stated that Stellantis N.V. (NYSE:STLA) has signed an MOU with Canadian armored-vehicle maker Roshel outlining a potential sale of its Brampton, Ontario ******* embly plant, which has been idle since 2023. According to union president Lana Payne, Stellantis N.V. (NYSE:STLA) has yet to provide the official year's notice required by the collective agreement. Payne described it as a "lose-lose scenario," claiming Stellantis' 2023 commitment to keep Brampton staffed had been broken.
The two stories are directly related. Brampton had been scheduled to build the Jeep Compass, with retooling beginning in early 2024 before Stellantis N.V. (NYSE:STLA) paused it in 2025 and then, that October, moved Compass manufacturing to the US completely, the same reassignment that sent the model to Belvidere.

#stellantis #NYSE

Gateway is paying tribute to the late Kyle Busch by introducing the track's new trophy prior to Sunday's NASCAR Cup Series race. Busch, who passed away suddenly on May 21, earned his 63rd and final Cup Series win at Gateway, also known as World Wide Technology Raceway, back in June 2023.
Gateway is calling it the "Rowdy" trophy, an homage to Busch's signature nickname he earned during his illustrious NASCAR career. The trophy will be presented to the winner of Sunday's Enjoy Illinois 300, which is the second race of the Chase.
In the media center at WTT Raceway sits the new "Rowdy Trophy" dedicated to the late Kyle Busch. Engraved on the trophy is a special message that reads:
"The Rowdy Trophy … In recognition of his contribution to the sport and his final win at WTT Raceway"
Jeff Gluck, motorsports writer for The Athletic, shared an up-close look at the trophy in a social media video.

#nascar

Princess Diana captivated the world in June 1994 when she arrived at a Vanity Fair gala wearing a bold, off-the-shoulder black silk dress by Christina Stambolian. That very same night, King Charles publicly admitted to being unfaithful to Diana during their marriage.
Diana's daring outfit dominated headlines and overshadowed Charles' confession, and thus, the ensemble was dubbed a "revenge dress."
More from StyleCaster
William Reportedly Didn't Want Diana's 'Memory' to Be Used as Meghan's 'Launching Pad' After the ****** ss's Alleged 'Vulgar Act' at His Late Mom's Gravesite
Kate Shares Telling Diana Message After Claims of Meghan's 'Vulgar Act' at the Late Princess' Gravesite

#charles #vulgar #june #fair

Carole Radziwill shared the backstory on how Kim Kardashian came to own the so-called "cursed" Cartier watch formerly belonging to Jackie Kennedy Onassis
The Bravo star came into possession of the watch when her late husband and nephew of Kennedy Onassis, Anthony Radziwill, gifted it to her for her 30th birthday
However, after seeing three women, including herself, become widowed after owning the accessory, she decided to put it up for auction through Christie's
Carole Radziwill went through a "series of very strange events" that pushed her to put Jackie Kennedy Onassis' beloved Cartier watch up for auction in 2017.
The writer and Bravo star, 63, inherited the former first lady's famous Cartier Tank watch for her 30th birthday during her marriage to Kennedy Onassis' nephew, Anthony Radziwill, who died of cancer in 1999; his father Prince Stanislaw Radziwill gifted the watch to Kennedy Onassis in 1963 and engraved it with "Stas to Jackie 23 Feb. 63 2:05 am to 9:35 pm" in reference to the 1963 50-Mile Hike in Palm Beach, according to Christie's, which ended up auctioning the piece.

#cartier #carole #bravo #anthony

Aston Villa v **** nal, August 2024. Morgan Rogers receives a pass facing his own goal and Declan Rice is immediately on his back, but the Villa midfielder takes the ball with the outside of his right foot and swivels into **** e, leaving Rice behind. The **** e is quickly filled by **** nal's midfield enforcer Thomas Partey, but Rogers knocks it past Partey and races around his back to regather the ball, leaving the Ghanaian splayed on the grass. Their tussle at least buys Rice some time to catch up, but as he lunges in to make the tackle, Rogers takes a clever touch and Rice concedes a clumsy foul.
Arsenal would go on to win but it was an afternoon full of moments like that one in which Rogers tormented his opponents. After the game, Mikel Arteta marvelled at his performance. On Sky Sports, Jamie Redknapp compared Rogers to "Jonah Lomu in his prime", and when you saw the trail of **** nal bodies left on the floor, you understood exactly what he meant.
The Lomu comparison touched on what makes Rogers rare, even unique, in world football, and perhaps helps to explain why Chelsea FC were prepared to spend £117m to sign him this summer. Rogers is a blend of football genres, a walking oxymoron, powerful and graceful, hardy and agile, heavy and light all at once, like some contorted beast with the shoulders of a buffalo and the feet of a squirrel on an errand.
Morgan Rogers has made an impressive start to life at Chelsea (Getty)
There are other robust ball-carriers at the top of the game: Antoine **** yo and Jude Bellingham come to mind; Ryan Gravenberch, Manu Kone and Rice all perform similar functions from deep. But none have Rogers' package of strength and balance, quick feet and rapid acceleration, that creative eye and subtle movement between the lines. In an increasingly **** genized world of coaching and industrialised talent production, Rogers is something of a unicorn forward.

#villa #partey

The Minnesota Vikings continue to be relatively healthy as Week 1 approaches. Jakobe Thomas, the team's third-round pick at safety, was the only player who didn't participate in Wednesday's practice due to an illness.
However, it appears Thomas has gotten past that. He was limited in Thursday's practice, as were fellow rookies Caleb Tiernan (ankle) and Jacob Thomas (ankle), the undrafted free-agent safety out of James Madison.
Green Bay's injury list was lengthier, with DL Warren Brinson and LB Ty'Ron Hopper listed as DNPs for the second straight day. Starters who were limited on Thursday included RT Zach Bako-Bewele (knee), LG Aaron Banks (knee), DL Devonte Wyatt (ankle), DL Javon Hargrave (knee), and EDGE Barryn Sorrell (foot).
Starting LT Jordan Morgan (knee) was upgraded to a full participant after being limited on Wednesday.
This article originally appeared on Vikings Wire: Thursday injury report for the Vikings Week 1 matchup

#thomas #thursday #safety #practice

Alexis Mac Allister has revealed that Liverpool told him the club were not in a position to renew his contract and that he had options to leave in the summer.
Mac Allister's current contract at Liverpool is set to expire in 2028 and discussions over a renewal have failed to reach an agreement.
The failed talks leave the Argentine in an uncertain situation, after teammates Dominik Szoboszlai and Ryan Gravenberch signed new long-term deals.
Mac Allister has revealed that Liverpool told his agents that the club were 'not in a position to renew' and has expressed his disappointment at the outcome of the talks.
Speaking to the media ahead of Liverpool'sChampions League clash with Atletico Madrid, Mac Allister said it was 'sad' that renewal talks did not lead to fresh terms.

#allister

Alexis Mac Allister has admitted he was left "very, very sad" after being told Liverpool were not in a position to offer him a new contract.
The midfielder ultimately decided to remain at Anfield this summer despite having opportunities to leave, and insists he will continue to give everything for the club.
But he says seeing team-mates Dominik Szoboszlai and Ryan Gravenberch sign new deals has made his own situation more difficult.
"There was a chance [I could have left the club in the summer]," Mac Allister said.
"As everyone knows, I received the news that the club was not in a position to offer me a new contract, which makes me very, very sad.

#allister #offer #contract #alexis

Now that Meghan Markle is back in the UK, there's a lot of interest in if she'll be keeping some of her Hollywood connections. A lot of big celebrities attended her wedding with Prince Harry, but not many were seen in the years after as they were living in the UK. Has the time in the US changed that?
Reportedly, not so much. At least not for one particular person. Markle was allegedly interested in having tea with Beyoncé and Jay-Z, who are in London for Jay-Z's Tottenham Hotspur Stadium shows. And yet no plans materialized for a meeting, casual or otherwise.
More from StyleCaster
Meghan Accused of More Controversial Diana Behavior After Claims of Her 'Vulgar Act' at Harry's Late Mom's Gravesite
Meghan Reportedly Refusing to 'Bow' to Kate When She Becomes Queen Amid Their 'Hostility'-She's Not Going to 'Beg for Forgiveness'

#reportedly #prince #harry #hotspur

Liverpool have a superstar who is worth £30m and more.
One area Liverpool will need to address over the coming months and potentially years is midfield, with the position largely overlooked during the latest transfer window.
The emergence of Trey Nyoni certainly played a part in that decision. Even after Curtis Jones' departure, Liverpool chose against bringing in another midfielder because of their belief that Nyoni can develop into a top-level player.
His recent cameos have certainly suggested he is ready to take that next step, but there are still plenty of questions surrounding the midfield long-term.
Ryan Gravenberch and Dominik Szoboszlai remain uncertain options in a double pivot, while Alexis Mac Allister's future is far from guaranteed. Liverpool may therefore need to revisit midfield sooner rather than later.

#midfield

MILAN (AP) — No longer a teenager, Kimi Antonelli is keen to show just how much he has progressed as he prepares for his home grand prix, even though he has to start at the back of the grid.
It was two years ago at Monza that Antonelli was given his Formula 1 debut but that lasted just 10 minutes as the youngster was involved in a high-speed crash in the first practice session for the Italian Grand Prix.
Now Antonelli, who turned 20 last week, arrives as championship leader.
"That definitely was not the way I wanted to introduce myself into the sport," Antonelli said. "If someone, while I was walking off in the gravel, would have said, 'in two years you're going to be leading the world championship in this exact moment,' I would have said 'shut up … don't joke with me.'
"But, you know, it's happening. And, you know, I'm very, very, very happy, very grateful. And just got to keep pushing."

#know

On August 26, Biohaven (NYSE:BHVN) and SK Biopharmaceuticals announced a global licensing agreement covering opakalim, Biohaven's lead epilepsy candidate, in a deal worth up to $795 million plus royalties. SK Biopharmaceuticals picks up exclusive worldwide rights to Biohaven's Kv7 ion channel platform, while Biohaven walks away with $400 million in near-term cash. The timing lines up with an August 10, 2026 earnings report that showed Biohaven still losing well over $100 million a quarter, and the gap between those two dates explains a lot about why this deal happened now.
SK Biopharmaceuticals will pay up to $795 million in upfront and milestone payments connected to the Kv7 platform, on top of tiered royalties on US net sales of opakalim that range from the mid-teens to low twenties. Biohaven collects $350 million at closing and another $50 million in 2027, with as much as $150 million more available through development and regulatory milestones plus royalties on global sales. SK Biopharmaceuticals is also taking over Kv7 program costs going forward, including certain Knopp Biosciences obligations. CEO Vlad Coric described the structure as proof Biohaven can monetize its pipeline through partnerships rather than leaning on public markets for cash.
The deal only makes sense because opakalim looks like it works. In a proof-of-concept study in idiopathic generalized epilepsy, the median time to a second generalized tonic-clonic seizure stretched to 141 days on opakalim versus 47 days on placebo, and a third of patients made it through the full 24 weeks without a second seizure. In focal epilepsy, 54% of patients in an open-label extension study saw at least a 50% drop in seizure frequency over any six months, in a group of more than 100 patients.
Opakalim is also designed as a once-daily pill with no ******* ration required, a real edge over older antiseizure drugs. Pairing that data with SK Biopharmaceuticals, the company behind XCOPRI and the only firm to bring a new focal-seizure drug to the US market since 2016, gives Opakalim a commercial path Biohaven would have struggled to build alone. The cash also buys runway for the rest of the pipeline, including protein degraders BHV-1300 and BHV-1400, which have shown rapid, selective reductions in disease-driving antibodies in Graves' disease and IgA nephropathy with clean safety data across nearly 200 patients dosed.
Biohaven is giving up full ownership of an ******* et it now believes could be a major seller. Royalties in the mid-teens to low twenties are real money, but they are a fraction of what outright ownership of an approved epilepsy drug would be worth, and $50 million of the $400 million upfront does not arrive until 2027. The Knopp Biosciences obligations SK Biopharmaceuticals is absorbing, worth up to $245 million plus mid-single-digit royalties, are a reminder that other parties already have claims on opakalim's future revenue before Biohaven sees a dollar of profit from it.

#ro

The Green Bay Packers appear to have the talent needed to challenge for the Super Bowl, giving the franchise a real opportunity to end its lengthy championship drought. Green Bay has not reached the Super Bowl since its 2010 ******* le run, but expectations are high that this roster could finally put the team back on that stage.
The Packers reshaped their defense during the offseason, adding Zaire Franklin at linebacker and Javon Hargrave along the interior of the defensive line. Both additions give Green Bay more depth and experience as the team navigates Micah Parsons' absence while he continues to recover from an ACL injury.
Talk of Green Bay making a move for Arizona Cardinals linebacker Josh Sweat appears to be unfounded. Packers general manager Brian Gutekunst dismissed the trade speculation outright, according to The Athletic's Matt Schneidman.
Feb 24, 2026; Indianapolis, IN, USA; Green Bay Packers general manager Brian Gutekunst speaks at the NFL Scouting Combine at the Indiana Convention Center. Mandatory Credit: Kirby Lee-Imagn Images
"Somebody's making stuff up," remarked the Packers GM when he was addressing the media.

#super #gutekunst #general

Celebrities have been everywhere this week. In New York City, Kacey Musgraves performs her Middle of Nowhere tour at Madison Square Garden, while Hugh Jackman attends The Death of Robin Hood screening in London.
Here are the best photos of celebs out and about this week. Come back tomorrow for more of the latest A-list outings!
01 of 120
Kacey Musgraves
Credit: Taylor Hill/WireImage
Kacey Musgraves continues her Middle of Nowhere tour with a stop at Madison Square Garden in New York City on Aug. 31.

#musgraves #madison

Eli Lilly and Company (NYSE:LLY) has agreed to acquire privately held Merida Biosciences for up to $2.875 billion in cash, including an upfront payment and milestone-based payments. The deal is expected to close in the fourth quarter of 2026.
The acquisition expands Lilly's immunology pipeline and gives it access to Merida's antibody-engineering platform, which is designed to selectively eliminate disease-causing autoantibodies while preserving normal immune function. Merida's lead candidate, MER511, is in Phase 1 development for Graves' disease and thyroid eye disease (TED). Early data showed substantial reductions in disease-related antibodies along with a favorable initial safety profile.
The deal also fits Eli Lilly and Company (NYSE:LLY)'s broader strategy of using the cash generated by its obesity and diabetes franchises to diversify into additional therapeutic areas. Lilly has been active in acquisitions throughout 2026, making Merida the latest addition to its expanding pipeline.
The biggest benefit for Eli Lilly and Company (NYSE:LLY) is pipeline diversification. The company has generated significant growth from Mounjaro and Zepbound, but that success also increases its reliance on the obesity and diabetes markets. Adding Merida gives Lilly another potential growth platform in immunology.
Merida's technology could be particularly valuable if it works beyond its lead program. Rather than broadly suppressing the immune system, its approach is designed to target the antibodies responsible for specific autoimmune and allergic diseases. This could potentially offer a more targeted treatment strategy and create opportunities across several conditions.

#lilly #NYSE #immunology

The Green Bay Packers' initial 53-man roster entering the 2026 season has been finalized, and it contains an oddity in that Green Bay opted to keep seven defensive tackles.
That is more than they have rostered in Brian Gutekunst's tenure as general manager and the most since 2013. It is a different world from where the Packers were a year ago, as the defensive tackle position looked thin entering the season and was decimated by the end of it.
The fact they have decided to keep so many this time around is perhaps a consequence of wanting to avoid such a situation again, but it is more so a testament to the work done to fortify the room this offseason, as well as some impressive growth by various preexisting players.
Javon Hargrave via free agency and Chris McClellan were the headline additions and along with Devonte Wyatt and Karl Brooks, made the position look stronger.
Beyond those four, no one else was certain of a roster spot entering training camp. In the end, so many other players impressed that the Packers had no choice but to keep seven.

#keep #defensive #position

With Liverpool already looking a little light in midfield following the sale of Curtis Jones to Inter Milan after the 25-year-old Scouser sought a move away from the club, a lot of fans would have been hoping for news of potential incomings before the transfer window slammed shut.
What they got instead Monday evening was word Nottingham Forest had submitted a £30M bid with £25M gaurunteed for talented 19-year-old midfielder Trey Nyoni, who impressed in pre-season for new head coach Andoni Iraola and was expected to be in his first team plans this season.
The upside is that almost immediately that news was followed up by confirmation that Liverpool had rejected the bid. More than that, the club have signalled that they won't consider any approach for Nyoni because he is in fact in Iraola's first team plans for the 2026-27 season.
Liverpool signed Nyoni out of Leicester City's academy in 2023, eventually paying around £1M after the case was sent to tribunal. The young midfielder has made 20 first team appearances to date over his three seasons at the club, with 14 of those (with six in the league) coming last season.
Nyoni was often deployed as the deepest midfielder, taking on the role Ryan Gravenberch will be expected to fill most often for the Reds this season, and with no further midfield signings expected at the moment it does seem likely he will see significant first team action over the next year.

#nyoni #midfielder

SARATOGA SPRINGS - Chalk up another one who fell to the "Graveyard of Champions."
Saratoga Race Course has long been known as the track where some of horse racing's greatest legends suffered their most surprising losses. Saturday, another superstar was defeated at the Spa, as Kentucky Derby and Belmont Stakes winner Golden Tempo could only muster a late-closing third in a Travers Stakes won by the inexperienced Leading Change, who was making just his third career start.
After winning the Derby and Belmont with similar late runs, Golden Tempo lingered at the back of the pack early in the Travers in company with his familiar rival, Renegade.
But unlike during the Triple Crown season, on Saturday the speed horses were able to hang on at the front of the field. Frontrunner Napoleon Solo held the lead deep into the stretch until the Brad **** -trained Leading Change, who sat second throughout the race under jockey Manny Franco, made his final surge to win by a half-length.
"The pace was slow, and I thought that was gonna be to our detriment," said Golden Tempo's trainer, Cherie DeVaux. "The horses in front of us are definitely quality horses … it didn't work out for us today."

#saratoga #belmont #tempo

CLEVELAND — Last summer, the Guardians found themselves embroiled in one of the wildest storylines around baseball, as closer Emmanuel Clase and starter Luis Ortiz were placed on leave for their alleged roles in a gambling scheme.
It's possible the Guardians might end up being involved in one of the oddest stories around the league in 2026 as well.
Major League Baseball reportedly opened an investigation and then suspended a sought-after Dominican prospect for an alleged scheme that included a fake name, age, birth certificate and even gravestone in order to falsify his identity and make him appear to be younger, according to an ESPN report.
David Severino was purportedly a switch-hitting infielder around the age of 14. He reportedly agreed to a $2.8 million deal with the Guardians that would be finalized in 2029, when he'd turn 17 and be eligible to sign.
But, it turns out his real name is Daury David Severino Damaso, and he's actually 16 years old, according to the reported investigation. Allegedly, with the consent of his parents and with the help of a trainer, the identity of David Severino Damaso was created to appear to be Daury's younger brother. A fake, late-filed birth registration was made under that name, along with falsified medical records.

#name #league