Aug 25 (Reuters) - Bristol Myers Squibb has ended its partnership with cell therapy startup Cellares to expand the ‌manufacturing of its personalized blood cancer therapy, a company ‌spokesperson told Reuters on Tuesday.
Bristol Myers determined that Cellares' cell therapy manufacturing platform, Cell Shuttle, could not meet the requirements to make its CAR-T therapy, Breyanzi, at commercial scale, the spokesperson said. Cellares did not immediately respond to a Reuters request for comment.
The development underscores ‌the challenges of manufacturing ⁠CAR-T therapies, a personalized form of cancer treatment that has transformed care for some blood cancer patients ⁠but remains difficult and expensive to produce.
Breyanzi, first approved by the U.S. FDA in 2021, is used to treat lymphoma and other blood cancers. It generated $1.36 billion in sales in 2025.
Endpoints News first ‌reported the development earlier in the day.

#cancer #breyanzi

Branden Jenkins was out to dinner when he pulled out his phone, glanced at his AI usage dashboard, and realized his weekend coding session had just cost him $1,000 — charged automatically, in $1,000 increments, to a card set on auto-renew.
Jenkins is the CEO of Maxio, a private-equity-backed software company headquartered in Atlanta that's on a path toward $100 million in annual revenue over the next couple of years. He's also, by his own admission, near the top of his company's internal AI spending leaderboard — an odd place for the chief executive to land. "A thousand is not that much, I would say, but for one weekend, it's pretty annoying," he said in an interview with Fortune. Describing his agent as "cooking away," he described his response as "Wow, I just got here quickly."
The episode has become something of a parable inside his company — and inside corporate America more broadly — for how quickly "agentic" AI tools can consume money without anyone quite noticing until the bill lands. But Jenkins said the surprise invoice isn't what's keeping him up at night. The deeper problem is something messier and more human: his own employees' "insecurity" about being outpaced by the technology — and by him.
Jenkins, a self-described technical CEO who builds his own agents and automations, said he can write code from his phone using Claude even while away from his desk — which is how he ended up debugging and iterating on a project at dinner. The token wallet he'd set up to fund those sessions was configured to auto-refill by $1,000 every time it ran dry, silently recharging his card without requiring a second thought — until he saw the total.
"I don't have governors where a lot of my staff hits limits, and they have to ask for approval," Jenkins said, describing his own unlimited internal budget as both a perk and a liability. "So I started leaning in and going, 'What does this look like?'"

#auto

Carlos Felipe Jaramillo-Grajales, a criminal illegal alien from Colombia, was recently sentenced to three years behind bars for identity theft and lying about his citizenship status — a falsification that, according to the Department of Homeland Security (DHS), he used to participate in U.S. elections over a period spanning roughly 20 years.
"Because of his fraud, he was able to obtain a driver's license and vote in our elections," DHS Secretary Markwayne Mullin said in a statement.
"DHS will always fight to protect the integrity of our elections, because election security is national security. Only Americans should be electing American leaders," he continued.
His Friday sentencing comes as lawmakers in Washington, D.C. have wrestled over whether new legislation is needed to shore up voter verification that demonstrates the lengths some aliens have gone to secure state ID.
Schumer Said 'Democrats Support Voter Id' — Then Every Senate Democrat Voted Against Gop Bill

#years #grajales #colombia #department