If you're trying to choose between the Vanguard S&P 500 ETF (NYSEMKT: VOO) and the State Street SPDR S&P 500 ETF (NYSEMKT: SPY), it might seem they're essentially interchangeable. They're both huge and track the same index.
At a high level, that's probably true. But if you want to dive deep and get picky, a few factors set them apart.
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The State Street SPDR S&P 500 ETF has an expense ratio of 0.0945%. The Vanguard S&P 500 ETF charges just 0.03%. Given that the index has historically returned about 10% per year, this fee difference may seem immaterial. But I will take any advantage I can get.
Because of their sizes, trading spreads (the difference between the buying (ask) price and the selling (bid) price of a stock) are virtually nothing, so spreads aren't really a consideration here. But if you can own the exact same index for a third of the cost, why not?

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